Sulfated Steroids: Ptilosteroids A-C and Ptilosaponosides A and B from the Solomon Islands Marine Sponge Ptilocaulis spiculifer

被引：18

作者：

Gabant, Marion ^{[1
]}

Schmitz-Afonso, Isabelle ^{[1
]}

Gallard, Jean-Francois ^{[1
]}

Menou, Jean-Louis ^{[2
]}

Laurent, Dominique ^{[3
]}

Debitus, Cecile ^{[4
]}

Al-Mourabit, Ali ^{[1
]}

机构：

[1] CNRS, ICSN, Ave Terrasse, F-91198 Gif Sur Yvette, France

[2] Ctr Noumea, IRD, Noumea, New Caledonia

[3] Univ Toulouse, IRD, Lab Pharmacochim Substances Naturelles & Pharmaco, UMR 152,UPS, F-31062 Toulouse 9, France

[4] Ctr Polynesien Rech Biodiversite Insulaire, UPS, IRD, UMR 152, F-98713 Papeete, Tahiti, France

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 04期

关键词：

PREGNANE STEROIDS; SOFT CORAL;

D O I：

10.1021/np800758c

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new pregnanes, ptilosteroid A (1), ptilosteroid B (2), and ptilosteroid C (3), and two new pregnane glycosides, ptilosaponoside A (4) and ptilosaponoside B (5), were isolated from the marine sponge Ptilocaulis spiculifer collected in the Solomon Islands. The structures were determined by spectroscopic methods. Biological tests of these compounds showed that they are not cytotoxic against KB cells.

引用

页码：760 / 763

页数：4

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