Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation

被引：33
作者：
Gilicze, Anna B. [1 ]
Wiener, Zoltan [1 ]
Toth, Sara [1 ]
Buzas, Edit [1 ]
Pallinger, Eva [1 ]
Falcone, Franco H. [2 ]
Falus, Andras [1 ]
机构：
[1] Semmelweis Univ, Dept Genet Cell & Immunobiol, H-1089 Budapest, Hungary
[2] Sch Pharm, Div Mol & Cellular Sci, Nottingham NG7 2RD, England
来源：
BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷
关键词：
C/EBP-ALPHA; EXPRESSION; INFLAMMATION; CELLS; DIFFERENTIATION; MIR-155; CANCER; GENE; PROLIFERATION; ACTIVATION;
D O I：
10.1155/2014/870267
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In the past few years expanding knowledge has been accumulated about the role of microRNAs (miRNAs) not only in hematopoiesis and cancer, but also in inflammatory and infectious diseases. Regarding myeloid cells, our knowledge is relatively insufficient, therefore we intended to collect the available data of miRNA profiles of myeloid cells. In addition to a rather general myeloid regulator miR-223, two other miRNAs seem to be useful subjects in understanding of myeloid miRNA biology: miR-27a and miR-652. We review functions of these three miRNAs and other myeloid miRNAs focusing on their roles in monocytes, neutrophils, eosinophils, basophils and mast cells.
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页数：9
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  • [1] Expression Profiling of Human Immune Cell Subsets Identifies miRNA-mRNA Regulatory Relationships Correlated with Cell Type Specific Expression
    Allantaz, Florence
    Cheng, Donavan T.
    Bergauer, Tobias
    Ravindran, Palanikumar
    Rossier, Michel F.
    Ebeling, Martin
    Badi, Laura
    Reis, Bernhard
    Bitter, Hans
    D'Asaro, Matilde
    Chiappe, Alberto
    Sridhar, Sriram
    Pacheco, Gonzalo Duran
    Burczynski, Michael E.
    Hochstrasser, Denis
    Vonderscher, Jacky
    Matthes, Thomas
    [J]. PLOS ONE, 2012, 7 (01):
  • [2] MicroRNAs: Genomics, biogenesis, mechanism, and function (Reprinted from Cell, vol 116, pg 281-297, 2004)
    Bartel, David P.
    [J]. CELL, 2007, 131 (04) : 11 - 29
  • [3] A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis
    Ben-Ami, Oren
    Pencovich, Niv
    Lotem, Joseph
    Levanon, Ditsa
    Groner, Yoram
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (01) : 238 - 243
  • [4] MicroRNA-21 inhibits toll-like receptor 2 agonist-induced lung inflammation in mice
    Case, Stephanie R.
    Martin, Richard J.
    Jiang, Di
    Minor, Maisha N.
    Chu, Hong Wei
    [J]. EXPERIMENTAL LUNG RESEARCH, 2011, 37 (08) : 500 - 508
  • [5] Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
    Chen, Xi
    Ba, Yi
    Ma, Lijia
    Cai, Xing
    Yin, Yuan
    Wang, Kehui
    Guo, Jigang
    Zhang, Yujing
    Chen, Jiangning
    Guo, Xing
    Li, Qibin
    Li, Xiaoying
    Wang, Wenjing
    Zhang, Yan
    Wang, Jin
    Jiang, Xueyuan
    Xiang, Yang
    Xu, Chen
    Zheng, Pingping
    Zhang, Juanbin
    Li, Ruiqiang
    Zhang, Hongjie
    Shang, Xiaobin
    Gong, Ting
    Ning, Guang
    Wang, Jun
    Zen, Ke
    Zhang, Junfeng
    Zhang, Chen-Yu
    [J]. CELL RESEARCH, 2008, 18 (10) : 997 - 1006
  • [6] MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment
    Dorhoi, Anca
    Iannaccone, Marco
    Farinacci, Maura
    Fae, Kellen C.
    Schreiber, Jorg
    Moura-Alves, Pedro
    Nouailles, Geraldine
    Mollenkopf, Hans-Joachim
    Oberbeck-Mueller, Dagmar
    Joerg, Sabine
    Heinemann, Ellen
    Hahnke, Karin
    Loewe, Delia
    Del Nonno, Franca
    Goletti, Delia
    Capparelli, Rosanna
    Kaufmann, Stefan H. E.
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (11) : 4836 - 4848
  • [7] MicroRNAs regulatory networks in myeloid lineage development and differentiation: regulators of the regulators
    El Gazzar, Mohamed
    McCall, Charles E.
    [J]. IMMUNOLOGY AND CELL BIOLOGY, 2012, 90 (06) : 587 - 593
  • [8] Complexity of miR-223 regulation by CEBPA in human AML
    Eyholzer, Marianne
    Schmid, Sabine
    Schardt, Julian A.
    Haefliger, Simon
    Mueller, Beatrice U.
    Pabst, Thomas
    [J]. LEUKEMIA RESEARCH, 2010, 34 (05) : 672 - 676
  • [9] A minicircuitry comprised of MicroRNA-223 and transcription factors NFI-A and C/EBPα regulates human granulopoiesis
    Fazi, F
    Rosa, A
    Fatica, A
    Gelmetti, V
    De Marchis, ML
    Nervi, C
    Bozzoni, I
    [J]. CELL, 2005, 123 (05) : 819 - 831
  • [10] MicroRNA-27 enhances differentiation of myeloblasts into granulocytes by post-transcriptionally downregulating Runx1
    Feng, Jue
    Iwama, Atsushi
    Satake, Masanobu
    Kohu, Kazuyoshi
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2009, 145 (03) : 412 - 423
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