Synthetic Lethality -- A New Direction in Cancer-Drug Development.

被引：174

作者：

Iglehart, J. Dirk ^{[1
,2
]}

Silver, Daniel P. ^{[3
]}

机构：

[1] Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA

[3] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dana Farber Canc Inst,Dept Med Oncol, Boston, MA 02115 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 361卷 / 02期

关键词：

HOMOLOGOUS RECOMBINATION; PARP INHIBITOR; SENSITIVITY; RESISTANCE; REPAIR; MUTATIONS; THERAPY; SCREEN;

D O I：

10.1056/NEJMe0903044

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：189 / 191

页数：3

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