Biosensors and their applications in detection of organophosphorus pesticides in the environment

被引：131

作者：

Hassani, Shokoufeh ^{[1
,6
]}

Momtaz, Saeideh ^{[1
,2
,6
]}

Vakhshiteh, Faezeh ^{[3
]}

Maghsoudi, Armin Salek ^{[1
,6
]}

Ganjali, Mohammad Reza ^{[4
,5
]}

Norouzi, Parviz ^{[4
,5
]}

Abdollahi, Mohammad ^{[1
,5
,6
]}

机构：

[1] Univ Tehran Med Sci, Fac Pharm, Pharmaceut Sci Res Ctr, Tehran 1417614411, Iran

[2] ACECR, Inst Med Plants, Med Plants Res Ctr, Karaj, Iran

[3] Univ Tehran Med Sci, Fac Pharm, Nanotechnol Res Ctr, Tehran, Iran

[4] Univ Tehran, Fac Chem, Ctr Excellence Electrochem, Tehran, Iran

[5] Univ Tehran Med Sci, Endocrinol & Metab Res Inst, Tehran, Iran

[6] Univ Tehran Med Sci, Universal Sci Educ & Res Network USERN, Toxicol Interest Grp, Tehran, Iran

来源：

ARCHIVES OF TOXICOLOGY | 2017年 / 91卷 / 01期

基金：

美国国家科学基金会;

关键词：

Organophosphorus pesticides (OPs); Biosensor detection of OPs; Nanomaterials; SURFACE-PLASMON RESONANCE; MOLECULARLY IMPRINTED POLYMER; FLUORESCENCE POLARIZATION IMMUNOASSAY; ARTIFICIAL NEURAL-NETWORKS; SOLID-PHASE EXTRACTION; CARBAMATE PESTICIDES; ELECTROCHEMICAL IMMUNOSENSOR; GOLD NANOPARTICLES; OXIDATIVE STRESS; PHOSPHORYLATED ACETYLCHOLINESTERASE;

D O I：

10.1007/s00204-016-1875-8

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

This review discusses the past and recent advancements of biosensors focusing on detection of organophosphorus pesticides (OPs) due to their exceptional use during the last decades. Apart from agricultural benefits, OPs also impose adverse toxicological effects on animal and human population. Conventional approaches such as chromatographic techniques used for pesticide detection are associated with several limitations. A biosensor technology is unique due to the detection sensitivity, selectivity, remarkable performance capabilities, simplicity and on-site operation, fabrication and incorporation with nanomaterials. This study also provided specifications of the most OPs biosensors reported until today based on their transducer system. In addition, we highlighted the application of advanced complementary materials and analysis techniques in OPs detection systems. The availability of these new materials associated with new sensing techniques has led to introduction of easy-to-use analytical tools of high sensitivity and specificity in the design and construction of OPs biosensors. In this review, we elaborated the achievements in sensing systems concerning innovative nanomaterials and analytical techniques with emphasis on OPs.

引用

页码：109 / 130

页数：22

共 195 条

[1] Determination of organophosphorus and carbamate pesticides using a piezoelectric biosensor [J].