Micro-magnetic imprinting of high field gradient magnetic flux sources

被引:40
作者
Dempsey, N. M. [1 ,2 ]
Le Roy, D. [1 ,2 ]
Marelli-Mathevon, H. [1 ,2 ]
Shaw, Gorky [1 ,2 ]
Dias, A. [1 ,2 ]
Kramer, R. B. G. [1 ,2 ]
Le Viet Cuong [1 ,2 ]
Kustov, M. [1 ,2 ]
Zanini, L. F. [1 ,2 ]
Villard, C. [1 ,2 ]
Hasselbach, K. [1 ,2 ]
Tomba, C. [1 ,2 ]
Dumas-Bouchiat, F. [1 ,2 ]
机构
[1] Univ Grenoble Alpes, Inst NEEL, F-38042 Grenoble, France
[2] CNRS, Inst NEEL, F-38042 Grenoble, France
关键词
CELLS; CHIP; PARTICLES;
D O I
10.1063/1.4886375
中图分类号
O59 [应用物理学];
学科分类号
摘要
We report here on the fabrication of hard magnetic powder based micro-flux sources using micro-patterned hard magnetic films as templates or master structures. The micro-magnetic imprinting (mu MI) process is simple and the constituent materials of the final structures, commercial hard magnetic powders and polymer, are inexpensive. The structures may be transparent, and either flexible or rigid, depending on the choice of polymer matrix used. The peak-to-peak intensity of the z-component of the stray magnetic field measured above a test mu MI structure made with spherical NdFeB particles of average particle size 16 mu m is in good agreement with simulated field values (150mT at 5 mu m). Simulations indicate magnetic field gradients of up to 5 x 10(5) T/m at the surface of such mu MI structures. The trapping of cells functionalised with superparamagnetic beads by these structures has been demonstrated. The mu MI fabrication technique has much potential for the development of high field gradient magnetic flux sources for applications in biology and beyond. (C) 2014 AIP Publishing LLC.
引用
收藏
页数:5
相关论文
共 36 条
  • [1] [Anonymous], 2012, U.S. patent, Patent No. [61/650,398, 61650398]
  • [2] Bowers B. J., 2007, TRANSDUCERS '07 & Eurosensors XXI. 2007 14th International Conference on Solid-State Sensors, Actuators and Microsystems, P1585, DOI 10.1109/SENSOR.2007.4300450
  • [3] Evolutionary conservation of early mesoderm specification by mechanotransduction in Bilateria
    Brunet, Thibaut
    Bouclet, Adrien
    Ahmadi, Padra
    Mitrossilis, Demosthene
    Driquez, Benjamin
    Brunet, Anne-Christine
    Henry, Laurent
    Serman, Fanny
    Bealle, Gaelle
    Menager, Christine
    Dumas-Bouchiat, Frederic
    Givord, Dominique
    Yanicostas, Constantin
    Le-Roy, Damien
    Dempsey, Nora M.
    Plessis, Anne
    Farge, Emmanuel
    [J]. NATURE COMMUNICATIONS, 2013, 4
  • [4] Multiscale immunomagnetic enrichment of circulating tumor cells: from tubes to microchips
    Chen, Peng
    Huang, Yu-Yen
    Hoshino, Kazunori
    Zhang, Xiaojing
    [J]. LAB ON A CHIP, 2014, 14 (03) : 446 - 458
  • [5] Microscale resin-bonded permanent magnets for magnetic micro-electro-mechanical systems applications
    Cho, HJ
    Ahn, CH
    [J]. JOURNAL OF APPLIED PHYSICS, 2003, 93 (10) : 8674 - 8676
  • [6] An on-chip magnetic bead separator using spiral electromagnets with semi-encapsulated permalloy
    Choi, JW
    Liakopoulos, TM
    Ahn, CH
    [J]. BIOSENSORS & BIOELECTRONICS, 2001, 16 (06) : 409 - 416
  • [7] Controlled transport of magnetic particles using soft magnetic patterns
    Conroy, Richard S.
    Zabow, Gary
    Moreland, John
    Koretsky, Alan P.
    [J]. APPLIED PHYSICS LETTERS, 2008, 93 (20)
  • [8] Dempsey N. M., 2013, PCT patent, Patent No. [WO2013174881 A1, 2013174881]
  • [9] Dempsey N. M., 2012, French patent, Patent No. [1,254,667, 1254667]
  • [10] Fabrication of magnetic microfiltration systems using soft lithography
    Deng, T
    Prentiss, M
    Whitesides, GM
    [J]. APPLIED PHYSICS LETTERS, 2002, 80 (03) : 461 - 463