Surgical approaches for lung volume reduction in emphysema

被引:44
作者
Clark, Samuel J. [1 ,2 ]
Zoumot, Zaid [1 ,2 ]
Bamsey, Olivia [1 ,2 ]
Polkey, Michael I. [1 ,2 ]
Dusmet, Michael [1 ,2 ]
Lim, Eric [1 ,2 ]
Jordan, Simon [1 ,2 ]
Hopkinson, Nicholas S. [1 ,2 ]
机构
[1] Royal Brompton & Harefield NHS Fdn Trust, NIHR Resp Biomed Res Unit, London, England
[2] Imperial Coll London, London, England
关键词
Lung volume reduction surgery; emphysema; under-treatment; risk; mortality; DISEASE; MORTALITY; TRIAL;
D O I
10.7861/clinmedicine.14-2-122
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Lung volume reduction surgery (LVRS) for chronic obstructive pulmonary disease (COPD) is recommended in both British and international guidelines because trials have shown improvement in survival in selected patients with poor baseline exercise capacity and upper lobe-predominant emphysema. Despite this, few procedures are carried out, possibly because of historical concerns about high levels of morbidity and mortality associated with the operation. The authors reviewed data on lung volume reduction procedures at their institution between January 2000 and September 2012. There were no deaths within 90 days of unilateral LVRS (n=81), bullectomy (n=20) or intracavity drainage procedures (n=14). These data suggest that concerns about surgical mortality should not discourage LVRS in selected patients with COPD, provided that it is undertaken within a multidisciplinary team environment involving appropriate patient selection.
引用
收藏
页码:122 / 127
页数:6
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