Reductive heterocyclizations via indium/iodine-promoted one-pot conversion of 2-nitroaryl aldehydes, ketones, and imines

被引：31

作者：

Han, Rongbi

Son, Kee In

Ahn, Gil Hwan

Jun, Young Moo

Lee, Byung Min

Park, Younbong

Kim, Byeong Hyo ^{[1
]}

机构：

[1] Kwangwoon Univ, Dept Chem, Seoul 139701, South Korea

[2] Yanbian Univ, MOE, Key Lab Organism Funct Factors Changbai Mt, Jilin 133002, Peoples R China

[3] Korea Res Inst Chem Technol, Taejon 305600, South Korea

[4] Chungnam Natl Univ, Dept Chem, Taejon 305764, South Korea

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 41期

基金：

新加坡国家研究基金会;

关键词：

indium and compounds; reduction; nitro compounds;

D O I：

10.1016/j.tetlet.2006.08.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Nitroaryl aldehydes, ketones, and imines were reductively cyclized to 2,1-benzisoxazoles with good yields in the presence of indium and iodine in MeOH. Under a similar condition, N-(2-nitrobenzylidene)anilines were produced mixtures of 2,1-benzisoxazoles and 3-anilino-2-phenyl-2H-indazoles. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：7295 / 7299

页数：5

共 39 条

[1] Metal-mediated entry to functionalized 3-substituted 3-hydroxyindolin-2-ones via regiocontrolled carbonylallylation, bromoallylation, 1,3-butadien-2-ylation, propargylation, or allenylation reactions of isatins in aqueous media [J].