Update on the management of early-stage breast cancer

被引:8
作者
Heilat, Ghaith Bahjat [1 ,2 ]
Brennan, Meagan E. [1 ,3 ,4 ]
French, James [4 ,5 ]
机构
[1] Westmead Hosp, Westmead Breast Canc Inst, Westmead, NSW, Australia
[2] Yarmouk Univ, Fac Med, Sch Med Clin Sci, Irbid, Jordan
[3] Univ Sydney, Sch Med, Fac Med & Hlth, Northern Clin Sch, Sydney, NSW, Australia
[4] Univ Sydney, Sch Med, Fac Med & Hlth, Western Clin Sch, Sydney, NSW, Australia
[5] Westmead Hosp, Westmead Breast Canc Inst, Breast Surg, Westmead, NSW, Australia
关键词
PATIENT-LEVEL METAANALYSIS; ADJUVANT ENDOCRINE THERAPY; CONSERVING SURGERY; SENTINEL-NODE; FOLLOW-UP; WOMEN; RECONSTRUCTION; NEOADJUVANT; IRRADIATION; TAMOXIFEN;
D O I
10.31128/AJGP-03-19-4891
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background Breast cancer affects one in eight Australian women. While surgery, chemotherapy, radiotherapy and endocrine therapy are still the main treatments, there have been changes in the sequencing of treatment and advances in each therapy. The general practitioner (GP) is involved at each stage of the patient's journey. Objective This article discusses the current approach to the management of early breast cancer. It focuses on changes in recent years and discusses the role of the GP in supporting women in their decision-making and treatment. Discussion Key changes include the increasing use of neoadjuvant chemotherapy, the development of advanced oncoplastic surgery and breast reconstruction techniques, the use of gene expression profiling and the recommendation for extended adjuvant endocrine therapy for up to 10 years.
引用
收藏
页码:604 / 608
页数:5
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