Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy

被引：57

作者：

Cao, Hongqian ^{[1
,2
]}

Yang, Yang ^{[2
]}

Liang, Minghui ^{[2
]}

Ma, Yuntian ^{[2
]}

Sun, Nan ^{[3
]}

Gao, Xibao ^{[1
]}

Li, Junbai ^{[3
]}

机构：

[1] Shandong Univ, Sch Publ Hlth, Jinan, Shandong, Peoples R China

[2] Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing, Peoples R China

[3] Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 02期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

TUMOR HYPOXIA;

D O I：

10.1039/d0cc07355e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polydopamine nanoparticles were used to stabilize a nano-Pt catalyst to relieve tumour hypoxia in photodynamic therapy (PDT). Polydopamine not only provides a platform for carrying nano-Pt and photosensitizers but is also used as a photothermal reagent for photothermal therapy (PTT). The system presented an enhanced anti-tumor therapy effect through a combined PDT and PTT mechanism.

引用

页码：255 / 258

页数：4

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