Visible-Light-Catalyzed Direct Benzylic C(sp3)-H Amination Reaction by Cross-Dehydrogenative Coupling

被引：145
作者：
Pandey, Ganesh [1 ]
Laha, Ramkrishna [1 ]
机构：
[1] Ctr Biomed Res CBMR, Mol Synth Lab, Lucknow 226014, Uttar Pradesh, India
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 49期
关键词：
amination; C-H functinalization; cross-coupling; photoredox catalysis; synthetic methods; C-H AMINATION; N BOND FORMATION; METAL-FREE; INTERMOLECULAR AMINATION; ORGANOCATALYTIC AMINATION; INTRAMOLECULAR AMINATION; HETEROCYCLE SYNTHESIS; OXIDATIVE SYNTHESIS; ALKYL ETHERS; BROMAMINE-T;
D O I：
10.1002/anie.201506990
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A conceptually new and synthetically valuable cross-dehydrogenative benzylic C(sp(3))-H amination reaction is reported by visible-light photoredox catalysis. This protocol employs DCA (9,10-dicyanoanthracene) as a visible-light-absorbing photoredox catalyst and an amide as the nitrogen source without the need of either a transition metal or an external oxidant.
引用
收藏
页码：14875 / 14879
页数：5
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