Facile Method for Preparation of Silica Coated Monodisperse Superparamagnetic Microspheres

被引：14

作者：

Pham, Xuan-Hung ^{[1
]}

Kyeong, San ^{[2
]}

Jang, Jaein ^{[3
]}

Kim, Hyung-Mo ^{[1
]}

Kim, Jaehi ^{[2
]}

Jung, Seunho ^{[1
]}

Lee, Yoon-Sik ^{[2
]}

Jun, Bong-Hyun ^{[1
]}

Chung, Woo-Jae ^{[3
]}

机构：

[1] Konkuk Univ, Dept Biosci & Biotechnol, Seoul 143701, South Korea

[2] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 151747, South Korea

[3] Sungkyunkwan Univ, Coll Biotechnol & Bioengn, Dept Genet Engn, Suwon 440746, South Korea

来源：

JOURNAL OF NANOMATERIALS | 2016年 / 2016卷

基金：

新加坡国家研究基金会;

关键词：

MAGNETIC NANOPARTICLES; CHROMATOGRAPHIC SEPARATION; MANIPULATION PLATFORM; SERS NANOPROBES; QUANTUM DOTS; CELL; IMMUNOASSAY; PERFORMANCE; FABRICATION; PARTICLES;

D O I：

10.1155/2016/1730403

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

This paper presents a facile method for preparation of silica coated monodisperse superparamagnetic microsphere. Herein, monodisperse porous polystyrene-divinylbenzene microbeads were prepared by seeded emulsion polymerization and subsequently sulfonated with acetic acid/H2SO4. The as-prepared sulfonated macroporous beads were magnetized in presence of Fe2+/Fe3+ under alkaline condition and were subjected to silica coating by sol-gel process, providing water compatibility, easily modifiable surface form, and chemical stability. FE-SEM, TEM, FT-IR, and TGA were employed to characterize the silica coated monodisperse magnetic beads (similar to 7.5 mu m). The proposed monodisperse magnetic beads can be used as mobile solid phase particles candidate for protein and DNA separation.

引用

页数：9

共 54 条

[1] A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening [J].

Alefantis, T ;

Grewal, P ;

Ashton, J ;

Khan, AS ;

Valdes, JJ ;

Del Vecchio, VG .

MOLECULAR AND CELLULAR PROBES, 2004, 18 (06) :379-382

[2] Bifunctional Au-Fe3O4 nanopartides for protein separation [J].

Bao, Jie ;

Chen, Wei ;

Liu, Taotao ;

Zhu, Yulin ;

Jin, Peiyuan ;

Wang, Leyu ;

Liu, Junfeng ;

Wei, Yongge ;

Li, Yadong .

ACS NANO, 2007, 1 (04) :293-298

[3] Effect of polystyrene-divinylbenzene resin sulfonation on solute retention in high-performance liquid chromatography [J].

Chambers, TK ;

Fritz, JS .

JOURNAL OF CHROMATOGRAPHY A, 1998, 797 (1-2) :139-147

[4] New magnetic tweezers for investigation of the mechanical properties of single DNA molecules [J].

Chiou, CH ;

Huang, YY ;

Chiang, MH ;

Lee, HH ;

Lee, GB .

NANOTECHNOLOGY, 2006, 17 (05) :1217-1224

[5] A micromachined DNA manipulation platform for the stretching and rotation of a single DNA molecule [J].

Chiou, CH ;

Lee, GB .

JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2005, 15 (01) :109-117

[6] Novel magnetic nanoparticles coated by benzene- and β-cyclodextrin-bearing dextran, and the sorption of polycyclic aromatic hydrocarbon [J].

Cho, Eunae ;

Tahir, Muhammad Nazir ;

Choi, Jae Min ;

Kim, Hwanhee ;

Yu, Jae-Hyuk ;

Jung, Seunho .

CARBOHYDRATE POLYMERS, 2015, 133 :221-228

[7] Fluorescent, Superparamagnetic Nanospheres for Drug Storage, Targeting, and Imaging: A Multifunctional Nanocarrier System for Cancer Diagnosis and Treatment [J].

Cho, Hoon-Sung ;

Dong, Zhongyun ;

Pauletti, Giovanni M. ;

Zhang, Jiaming ;

Xu, Hong ;

Gu, Hongchen ;

Wang, Lumin ;

Ewing, Rodney C. ;

Huth, Christopher ;

Wang, Feng ;

Shi, Donglu .

ACS NANO, 2010, 4 (09) :5398-5404

[8] Biocompatible heterostructured nanoparticles for multimodal biological detection [J].

Choi, Jin-sil ;

Jun, Young-wook ;

Yeon, Soo-In ;

Kim, Hyoung Chan ;

Shin, Jeon-Soo ;

Cheon, Jinwoo .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (50) :15982-15983

[9] Macroporous Fe3O4/Carbon Composite Microspheres with a Short Li+ Diffusion Pathway for the Fast Charge/Discharge of Lithium Ion Batteries [J].

Choi, Seung Ho ;

Ko, You Na ;

Jung, Kyeong Youl ;

Kang, Yun Chan .

CHEMISTRY-A EUROPEAN JOURNAL, 2014, 20 (35) :11078-11083

[10] Engineering Transaminase for Stability Enhancement and Site-Specific Immobilization through Multiple Noncanonical Amino Acids Incorporation [J].

Deepankumar, Kanagavel ;

Nadarajan, Saravanan Prabhu ;

Mathew, Sam ;

Lee, Sun-Gu ;

Yoo, Tae Hyeon ;

Hong, Eun Young ;

Kim, Byung-Gee ;

Yun, Hyungdon .

CHEMCATCHEM, 2015, 7 (03) :417-421

← 1 2 3 4 5 6 →