Current applications and future prospects of nanomaterials in tumor therapy

被引:60
作者
Huang, Yu [1 ]
Fan, Chao-Qiang [1 ]
Dong, Hui [1 ]
Wang, Su-Min [1 ]
Yang, Xiao-Chao [2 ]
Yang, Shi-Ming [1 ]
机构
[1] Third Mil Med Univ, Xinqiao Hosp, Dept Gastroenterol, Xinqiao St, Chongqing 400037, Peoples R China
[2] Third Mil Med Univ, Sch Biomed Engn, Dept Biomed Mat Sci, 30 Gaotanyan St, Chongqing 400038, Peoples R China
关键词
tumor; nanomaterials; nanoparticles; nanotechnology; WALLED CARBON NANOTUBES; CERIUM OXIDE NANOPARTICLES; NANOSCALE DRUG-DELIVERY; HUMAN PANCREATIC-CANCER; GOLD NANOPARTICLES; BIOMEDICAL APPLICATIONS; PHOTOTHERMAL THERAPY; GRAPHENE OXIDE; QUANTUM DOTS; HEPATOCELLULAR-CARCINOMA;
D O I
10.2147/IJN.S127349
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Tumors are one of the most serious human diseases and cause numerous global deaths per year. In spite of many strategies applied in tumor therapy, such as radiation therapy, chemotherapy, surgery, and a combination of these treatments, tumors are still the foremost killer worldwide among human diseases, due to their specific limitations, such as multidrug resistance and side effects. Therefore, it is urgent and necessary to develop new strategies for tumor therapy. Recently, the fast development of nanoscience has paved the way for designing new strategies to treat tumors. Nanomaterials have shown great potential in tumor therapy, due to their unique properties, including passive targeting, hyperthermia effects, and tumor-specific inhibition. This review summarizes the recent progress using the innate antitumor properties of metallic and nonmetallic nanomaterials to treat tumors, and related challenges and prospects are discussed.
引用
收藏
页码:1815 / 1825
页数:11
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