Sugar amide-pyrrolidine catalyst for the asymmetric Michael addition of ketones to nitroolefins

被引：25
作者：
Kumar, Togapur Pavan [1 ]
Balaji, Sirinyam Venugopal [1 ]
机构：
[1] CSIR Indian Inst Chem Technol, Div Nat Prod Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON-ASYMMETRY | 2014年 / 25卷 / 05期
关键词：
ENANTIOSELECTIVE CONJUGATE ADDITION; BETA-NITROSTYRENES; ALDOL REACTIONS; NITRO-MICHAEL; BIFUNCTIONAL ORGANOCATALYSTS; EFFICIENT ORGANOCATALYSTS; RECYCLABLE ORGANOCATALYST; CYCLIC-KETONES; IONIC LIQUIDS; ALDEHYDES;
D O I：
10.1016/j.tetasy.2014.02.003
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
New sugar amide-pyrrolidine derivatives possessing the furano form of the carbohydrate template were designed and developed as efficient and stereoselective organocatalysts for asymmetric Michael additions of ketones to nitroolefins at room temperature. Good yields and high selectivities were achieved with catalyst 2 under solvent-free and additive-free reaction conditions. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：473 / 477
页数：5
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