Malignant Peripheral Nerve Sheath Tumor of the Breast in a Patient without Neurofibromatosis: A Case Report

被引：6

作者：

Yi, Jeong Min ^{[1
]}

Moon, Eun Jeong ^{[1
]}

Oh, Se Jeong ^{[1
]}

Lee, Ahni ^{[2
]}

Suh, Young Jin ^{[1
]}

Baek, Jong Min ^{[1
]}

Choi, Seung Hye ^{[1
]}

Jung, Sang Seol ^{[1
]}

机构：

[1] Catholic Univ Korea, Dept Surg, Seoul, South Korea

[2] Catholic Univ Korea, Dept Pathol, Seoul, South Korea

来源：

JOURNAL OF BREAST CANCER | 2009年 / 12卷 / 03期

关键词：

Breast; Nerve sheath neoplasms; SCHWANNOMA; SURVIVAL;

D O I：

10.4048/jbc.2009.12.3.223

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Malignant peripheral nerve sheath tumors (MPNSTs) are malignant variants of peripheral nerve sheath tumors that develop at major or minor peripheral nerve branches or at the sheaths of peripheral nerve fibers. These tumors are derived from Schwann cells or pluripotent cells of a neural crest origin. Malignant tumors of the peripheral nerve sheath are most commonly seen in deeper soft tissues, and usually in the proximity of a nerve trunk. MPNSTs of the breast are very uncommon and they have rarely been reported on. We report here on a case of MPNST of the breast in a 59-year-old female who presented with a painless breast lump for two months. The excisional biopsy revealed a malignant peripheral nerve sheath tumor based on the microscopic findings and immunohistochemical staining. We performed Wide excision of breast tissue around the biopsy site and thereafter the patient underwent radiation therapy. The patient remains well without signs of recurrence 1 year following surgery.

引用

页码：223 / 226

页数：4

共 17 条

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