Three-Component One-Pot Synthesis of Indolo[3,4-a]acridine Derivatives with High Regioselectivity under Catalyst-Free Conditions

被引：9

作者：

Zhang, Mei-Mei ^{[1
]}

Wang, Wei ^{[2
]}

Wang, Xiang-Shan ^{[1
,2
]}

机构：

[1] Jiangsu Normal Univ, Key Lab Biotechnol Med Plant Jiangsu Prov, Xuzhou 221116, Jiangsu, Peoples R China

[2] Jiangsu Normal Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷

基金：

中国国家自然科学基金;

关键词：

ANALOGS; ACRONYCINE; MECHANISM; AGENTS;

D O I：

10.1002/jhet.1896

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three-component reaction of aldehyde, 9-ethyl-9H-carbazol-3-amine, and 5,5-dimethyl cyclohexane-1,3-dione under catalyst-free conditions in EtOH, regioselectivity gave corresponding indolo[3,4-a]acridine rather than indolo[2,3-b]acridine derivatives in high yields, which is confirmed by X-ray diffraction analysis.

引用

页码：E349 / E353

页数：5

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