Relationship between IL-6 and COVID-19: to be considered during treatment

被引：41
作者：
Vatansever, Hafize Seda [1 ,2 ]
Becer, Eda [2 ,3 ]
机构：
[1] Manisa Celal Bayar Univ, Fac Med, Dept Histol & Embryol, Manisa, Turkey
[2] East Univ, DESAM Inst, Mersin 10, Nicosia, Turkey
[3] East Univ, Fac Pharm, Dept Biochem, Mersin 10, Nicosia, Turkey
来源：
FUTURE VIROLOGY | 2020年 / 15卷 / 12期
关键词：
COVID-19; cytokine; cytokine storm; IL-6; SARS-CoV-2; NF-KAPPA-B; MANAGEMENT; CYTOKINES; CELLS;
D O I：
10.2217/fvl-2020-0168
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The detection and control of pro-inflammatory response is crucial in the early stages of viral infection. Coronavirus disease 2019 (COVID-19) is an emerging viral disease of global concern and optimal treatment has yet to be determined. Unknown response of treatment of COVID-19 is important during patient monitoring. IL-6 is one of the key cytokines after activated macrophages. Therefore, control of systemic IL-6 levels in SARS-CoV-2 infected patients may be a parameter for COVID-19 disease. This review is focused on the induction of IL-6 after viral infections as a target molecule for monitoring cellular response.
引用
收藏
页码：817 / 822
页数：6
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