Stapled peptide inhibitors of mutant estrogen receptor/coactivator interactions

被引:0
|
作者
Speltz, Thomas E. [1 ]
Danes, Jeanne M. [1 ]
Fanning, Sean W. [1 ]
Mayne, Christopher G. [2 ]
Tajkhorshid, Emad [2 ]
Greene, Geoffrey L. [1 ]
Frasor, Jonna M. [1 ]
Moore, Terry W. [1 ]
机构
[1] Univ Illinois, Chicago, IL USA
[2] Univ Illinois, Urbana, IL USA
关键词
D O I
10.1158/1538-7445.AM2018-1810
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1810
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Steroid receptor/coactivator binding inhibitors: An update
    Skowron, Kornelia J.
    Booker, Kenneth
    Cheng, Changfeng
    Creed, Simone
    David, Brian P.
    Lazzara, Phillip R.
    Lian, Amy
    Siddiqui, Zamia
    Speltz, Thomas E.
    Moore, Terry W.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2019, 493
  • [42] Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex
    Burakov, D
    Wong, CW
    Rachez, C
    Cheskis, BJ
    Freedman, LP
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (27) : 20928 - 20934
  • [43] Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator
    McInerney, EM
    Tsai, MJ
    OMalley, BW
    Katzenellenbogen, BS
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (19) : 10069 - 10073
  • [44] Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
    Leduc, AM
    Trent, JO
    Wittliff, JL
    Bramlett, KS
    Briggs, SL
    Chirgadze, NY
    Wang, Y
    Burris, TP
    Spatola, AF
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (20) : 11273 - 11278
  • [45] Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries:: Discovery of peptide antagonists of estrogen receptors α and β
    Chang, CY
    Norris, JD
    Gron, H
    Paige, LA
    Hamilton, PT
    Kenan, DJ
    Fowlkes, D
    McDonnell, DP
    MOLECULAR AND CELLULAR BIOLOGY, 1999, 19 (12) : 8226 - 8239
  • [46] Small molecule inhibitors of estrogen receptor a/coactivator binding: Synthesis and in vitro and cell-based biological evaluation
    Sun, Aiming
    Moore, Terry
    Gunther, Jillian R.
    Kim, Mi-Sun
    Rhoden, Eric
    Du, Yuhong
    Fu, Haian
    Snyder, James P.
    Katzenellenbogen, John A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [47] Implications of the binding of tamoxifen to the coactivator recognition site of the estrogen receptor
    Kojetin, Douglas J.
    Burris, Thomas P.
    Jensen, Elwood V.
    Khan, Sohaib A.
    ENDOCRINE-RELATED CANCER, 2008, 15 (04) : 851 - 870
  • [48] Identification of the MLL2 complex as a coactivator for estrogen receptor α
    Mo, Rigen
    Rao, Sambasiva M.
    Zhu, Yi-Jun
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (23) : 15714 - 15720
  • [49] Coactivator Function Defines the Active Estrogen Receptor Alpha Cistrome
    Lupien, Mathieu
    Eeckhoute, Jerome
    Meyer, Clifford A.
    Krum, Susan A.
    Rhodes, Daniel R.
    Liu, X. Shirley
    Brown, Myles
    MOLECULAR AND CELLULAR BIOLOGY, 2009, 29 (12) : 3413 - 3423
  • [50] Coactivator proteins as determinants of estrogen receptor structure and function: Spectroscopic evidence for a novel coactivator-stabilized receptor conformation
    Tamrazi, A
    Carlson, KE
    Rodriguez, AL
    Katzenellenbogen, JA
    MOLECULAR ENDOCRINOLOGY, 2005, 19 (06) : 1516 - 1528