High-resolution 2D NMR spectra in inhomogeneous fields via 3D acquisition

被引：2

作者：

Lin, Yanqin ^{[1
]}

Wei, Zhiliang ^{[1
]}

Zhang, Liandi ^{[1
]}

Lin, Liangjie ^{[1
]}

Chen, Zhong ^{[1
]}

机构：

[1] Xiamen Univ, Dept Elect Sci, Fujian Prov Key Lab Plasma & Magnet Resonance, State Key Lab Phys Chem Solid Surface, Xiamen 361005, Fujian, Peoples R China

来源：

CHEMICAL PHYSICS LETTERS | 2014年 / 599卷

关键词：

ZERO-QUANTUM-COHERENCE; MAGNETIC-FIELDS; IN-VIVO; SPECTROSCOPY; H-1-NMR; BRAIN; DIFFUSION; SECSY; B-0;

D O I：

10.1016/j.cplett.2014.03.019

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical studies. Here, a pulse sequence, based on coherence transfer module of tracking differences of precession frequencies of two spins and spin echo module, is proposed to obtain two dimension (2D) high-resolution NMR spectra via 3D acquisition under large field inhomogeneity. The proposed scheme composes of simple hard pulses and rectangle gradients. Resulting 2D spectra exhibit chemical shift differences and J coupling splittings in two orthogonal dimensions. The method developed here may offer a promising way for in situ high-resolution NMR studies on combinatorial chemistry. (C) 2014 Elsevier B. V. All rights reserved.

引用

页码：44 / 50

页数：7

共 39 条

[1] Localized intermolecular zero-quantum coherence spectroscopy in vivo [J].

Balla, David Z. ;

Faber, Cornelius .

CONCEPTS IN MAGNETIC RESONANCE PART A, 2008, 32A (02) :117-133

[2] Mobile single-sided NMR [J].

Bluemich, B. ;

Perlo, J. ;

Casanova, F. .

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 2008, 52 (04) :197-269

[3] Selective intermolecular zero-quantum coherence in high-resolution NMR under inhomogeneous fields [J].

Chen, Z ;

Hou, T ;

Chen, ZW ;

Hwang, DW ;

Hwang, LP .

CHEMICAL PHYSICS LETTERS, 2004, 386 (1-3) :200-205

[4] High-resolution NMR spectra in inhomogeneous fields via IDEAL (intermolecular dipolar-interaction enhanced all lines) method [J].

Chen, Z ;

Chen, ZW ;

Zhong, JH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (02) :446-447

[5] High resolution NMR spectroscopy of rat brain in vivo through indirect zero-quantum-coherence detection [J].

de Graaf, Robin A. ;

Rothman, Douglas L. ;

Behar, Kevin L. .

JOURNAL OF MAGNETIC RESONANCE, 2007, 187 (02) :320-326

[6] Indirect detection of NMR via geometry-dependent dipolar fields, revisited [J].

Dong, Wei ;

Meriles, C. A. .

JOURNAL OF MAGNETIC RESONANCE, 2007, 186 (02) :330-336

[7] Detection of long-range dipole-dipole interactions between nuclear spins in distant solids [J].

Dong, Wei ;

Meriles, Carlos A. .

CHEMICAL PHYSICS LETTERS, 2009, 470 (4-6) :313-317

[8] Studies of Secondary Melanoma on C57BL/6J Mouse Liver Using H-1 NMR Metabolomics [J].

Feng, Ju ;

Isern, Nancy G. ;

Burton, Sarah D. ;

Hu, Jian Zhi .

METABOLITES, 2013, 3 (04) :1011-1035

[9] The acquisition of multidimensional NMR spectra within a single scan [J].

Frydman, L ;

Scherf, T ;

Lupulescu, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (25) :15858-15862

[10] A new detection scheme for ultrafast 2D J-resolved spectroscopy [J].

Giraudeau, Patrick ;

Akoka, Serge .

JOURNAL OF MAGNETIC RESONANCE, 2007, 186 (02) :352-357

← 1 2 3 4 →