A stepwise one pot synthesis of alkyl thiophosphoramidate derivatives of nucleosides

被引：9

作者：

Miao, ZW ^{[1
]}

Fu, H ^{[1
]}

Han, B ^{[1
]}

Chen, Y ^{[1
]}

Zhao, YF ^{[1
]}

机构：

[1] Tsing Hua Univ, Sch Life Sci & Engn, Dept Chem, Minist Educ,Key Lab Bioorgan Phosphorus Chem, Beijing 100084, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 08期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1081/SCC-120003605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel alkyl thiophosphoramidate derivatives of nucleoside analogues as membrane-soluble prodrugs of the bioactive free nucleotides have been prepared by phosphochloridothioate chemistry.

引用

页码：1159 / 1167

页数：9

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