Near-infrared small molecular fluorescent dyes for photothermal therapy

被引：146

作者：

Chen, Yisha ^{[1
]}

Li, Li ^{[1
]}

Chen, Weijie ^{[2
]}

Chen, Haiyan ^{[1
]}

Yin, Jun ^{[2
]}

机构：

[1] China Pharmaceut Univ, State Key Lab Nat Med, Sch Engn, Dept Biomed Engn, Nanjing 210009, Jiangsu, Peoples R China

[2] Cent China Normal Univ, Key Lab Pesticide & Chem Biol,Coll Chem, Hubei Int Sci & Technol Cooperat Base Pesticide &, Minist Educ,Int Joint Res Ctr Intelligent Biosens, Wuhan 430079, Hubei, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2019年 / 30卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Near-infrared fluorescent dyes; Photothermal therapy; Cyanine; BODIPY; Phthalocyanine; TARGETED SMALL-MOLECULE; RECENT PROGRESS; FAR-RED; IN-VIVO; PROBE; CHEMOTHERAPY; PHTHALOCYANINE; SENSITIZATION; TUMORS;

D O I：

10.1016/j.cclet.2019.02.003

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Near-infrared (NIR) fluorescent dyes based on small organic molecules are characterized with low cytotoxicity, good biocompatibility and minimum interference from auto-fluorescence background, which are widely used in tumor diagnosis. Intensive research on molecular properties and photothermal properties of fluorescent dyes have been explored for non-invasive photothermal treatment of cancer. In this review, we focus on the development of imaging-induced photothermal therapy of small molecules and classification according to the structures of organic molecules including cyanines, phthalocyanines, rhodamine analogues and BODIPYs. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：1353 / 1360

页数：8

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