Indigenous Drugs in Ischemic Heart Disease in Patients with Diabetes

被引:13
作者
Dwivedi, Shridhar
Aggarwal, Amitesh [1 ]
机构
[1] Univ Delhi, Univ Coll Med Sci, Dept Med Prevent Cardiol, Delhi 110095, India
关键词
INHIBIT PLATELET-AGGREGATION; MOMORDICA-CHARANTIA; EUGENIA-JAMBOLANA; HIGH-FAT; EXPERIMENTAL ATHEROSCLEROSIS; ARACHIDONIC-ACID; AQUEOUS EXTRACTS; AEGLE-MARMELOS; GLOBAL BURDEN; RISK-FACTORS;
D O I
10.1089/acm.2009.0187
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Background: India is currently facing the silent epidemic of ischemic heart disease, type 2 diabetes mellitus (T2DM), hypertension, and stroke. Both diabetes and ischemic heart disease appear in Indian people a decade earlier compared to whites. The recent evidence that certain medicinal plants possess hypoglycemic, lipid-lowering, and immunomodulating properties on account of their rich flavonoid and/or other glucose-lowering active constituents merits scientific scrutiny in this regard. Objectives: The present communication aims to give a brief review of those plants that could be useful in T2DM associated with hypertension, ischemic heart disease, and/or dyslipidemia. Methods: Aegle marmelos (bael), Allium sativum (garlic), Curcuma domestica (turmeric), Eugenia jambolana (jamun), Murraya koenigii (curry leaves), Trigonella foenum graecum (fenugreek), and Terminalia arjuna (arjun) have been found to be useful in diabetes associated with ischemic heart disease. Their active biomolecules have been identified. They have also been demonstrated to be safe in long-term use. Conclusions: Further clinical research regarding their potency and efficacy vis-a-vis oral hypoglycemics needs to done.
引用
收藏
页码:1215 / 1221
页数:7
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