Metaplastic carcinoma (carcinosarcoma) of the breast: a case report

Metaplastic breast carcinoma (MBC) is a rare malignancy and accounting for less than 1% of all breast carcinomas, which is often composed of epithelial and mesenchymal components. The present study describes a case of a 43-year-old female patient with MBC, which is diagnosed according to the combination of the gross examination, ultrasonic, mammographic, magnetic resonance (MR), breast-specific gamma-imaging (BSGI) and sentinel lymph node biopsy. After undergoing lumpectomy of right breast, the patient received six courses of adjuvant chemotherapy and now undergoing radiotherapy, without any sign of recurrence or metastasis. MBC may have poorer prognosis compared with invasive breast cancer (IBC) but there is no standardized therapeutic strategy for it. It is urgently needed that large studies are conducted to investigate different treatment.