Palladium-catalyzed regioselective synthesis of benzosultams from functionalized ynamides and benzotriazoles/tetrazoles

被引：12

作者：

Reddy, Alla Siva ^{[1
]}

Kumari, A. Leela Siva ^{[1
]}

Swamy, K. C. Kumara ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON | 2017年 / 73卷 / 19期

关键词：

Ynamides; Benzotriazoles; Pd]-catalysis; Cyclization; Benzosultams; BIOLOGICAL-ACTIVITY; DERIVATIVES; ALKENES; SYSTEMS;

D O I：

10.1016/j.tet.2017.03.070

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed highly regioselective synthesis of benzotriazole appended benzosultams by the tandem-cyclization of functionalized ynamides with benzotriazoles has been accomplished. This transformation involves the formation of both C-N and C-C bonds in a single step. Donor solvents appear to enhance the yields of the products. The methodology is also applicable for the generation of triazole/tetrazole appended benzosultams. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：2766 / 2773

页数：8

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