Palladium-catalyzed regioselective synthesis of benzosultams from functionalized ynamides and benzotriazoles/tetrazoles

被引：12
作者：
Reddy, Alla Siva [1 ]
Kumari, A. Leela Siva [1 ]
Swamy, K. C. Kumara [1 ]
机构：
[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India
来源：
TETRAHEDRON | 2017年 / 73卷 / 19期
关键词：
Ynamides; Benzotriazoles; Pd]-catalysis; Cyclization; Benzosultams; BIOLOGICAL-ACTIVITY; DERIVATIVES; ALKENES; SYSTEMS;
D O I：
10.1016/j.tet.2017.03.070
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed highly regioselective synthesis of benzotriazole appended benzosultams by the tandem-cyclization of functionalized ynamides with benzotriazoles has been accomplished. This transformation involves the formation of both C-N and C-C bonds in a single step. Donor solvents appear to enhance the yields of the products. The methodology is also applicable for the generation of triazole/tetrazole appended benzosultams. (C) 2017 Elsevier Ltd. All rights reserved.
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收藏
页码：2766 / 2773
页数：8
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