Two-dimensional and quasi-three-dimensional dosimetry of hadron and photon beams with the Magic Cube and the Pixel Ionization Chamber

被引:27
作者
Cirio, R
Garelli, E
Schulte, R
Amerio, S
Boriano, A
Bourhaleb, F
Coutrakon, G
Donetti, M
Giordanengo, S
Koss, P
Madon, E
Marchetto, F
Nastasi, U
Peroni, C
Santuari, D
Sardo, A
Scielzo, G
Stasi, M
Trevisiol, E
机构
[1] Univ Turin, Expt Phys Dept, I-10125 Turin, Italy
[2] Ist Nazl Fis Nucl, I-10125 Turin, Italy
[3] ASP, I-10125 Turin, Italy
[4] Loma Linda Univ, Med Ctr, Loma Linda, CA 92354 USA
[5] S Giovanni AS Hosp, I-10100 Turin, Italy
[6] Fdn TERA, I-28100 Novara, Italy
[7] Fdn CNAO, I-20123 Milan, Italy
[8] OIRM S Anna, I-10126 Turin, Italy
[9] Candiolo TO & Mauriziano Hosp, UOA Fis Sanitaria, Inst Canc Res & Treatment IRCC, Turin, Italy
关键词
D O I
10.1088/0031-9155/49/16/017
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with water-equivalent slabs. The parallel plate ionization chambers have a sensitive area of 24 x 24 cm(2), and consist of 0.375 cm wide and 24 cm long strips. There are a total of 64 strips per chamber. The Magic Cube has been tested with the clinical proton beam at Loma Linda University Medical Centre (LLUMC), and was shown to be capable of fast and precise quasi-3D dose verification. The Pixel Ionization Chamber (PXC) is a detector with pixel anode segmentation. It is a 32 x 32 matrix of 1024 cylindrical ionization cells arranged in a square 24 x 24 cm(2) area. Each cell has 0.4 cm diameter and 0.55 cm height, at a pitch of 0.75 cm separates the centre of adjacent cells. The sensitive volume of each single ionization cell is 0.07 cm(3). The detectors are read out using custom designed front-end microelectronics and a personal computer-based data acquisition system. The PXC has been used to verify dynamic intensity-modulated radiotherapy for head-and-neck and breast cancers.
引用
收藏
页码:3713 / 3724
页数:12
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