Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes

被引:554
作者
Breivik, H. [1 ,2 ]
Cherny, N. [3 ]
Collett, B. [4 ]
de Conno, F. [5 ]
Filbet, M. [6 ]
Foubert, A. J. [7 ]
Cohen, R. [8 ]
Dow, L. [8 ]
机构
[1] Univ Oslo, Fac Med, Dept Anaesthesiol, Rikshosp, N-0027 Oslo, Norway
[2] Univ Hosp, Rikshosp, Dept Anaesthesiol, Oslo, Norway
[3] Shaare Zedek Med Ctr, Canc Pain & Palliat Med Serv, Jerusalem, Israel
[4] Univ Hosp Leicester NHS Trust, Pain Management Serv, Leicester, Leics, England
[5] Natl Canc Inst Fdn, Rehabil & Palliat Care Unit, Milan, Italy
[6] HCL CHU Lyon, Ctr Hosp Lyon Sud, Ctr Soins Palliatifs, Pierre Benite, France
[7] Erasmushogesch, Dept Gezondheidszorg, Brussels, Belgium
[8] Mundipharma Int Ltd, Cambridge, England
关键词
cancer pain; chronic pain; Europe; impact of pain; survey; treatment of pain; MANAGEMENT; OUTPATIENTS; MULTICENTER; BARRIERS; ISSUES;
D O I
10.1093/annonc/mdp001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Patients and methods: Patients with all stages of cancer participated in a two-phase telephone survey conducted in 11 European countries and Israel in 2006-2007. The survey screened for patients experiencing pain at least weekly, then randomly selected adult patients with pain of at least moderate intensity occurring several times per week for the last month completed a detailed attitudinal questionnaire. Results: Of 5084 adult patients contacted, 56% suffered moderate-to-severe pain at least monthly. Of 573 patients randomly selected for the second survey phase, 77% were receiving prescription-only analgesics, with 41% taking strong opioids either alone or with other drugs for cancer-related pain. Of those prescribed analgesics, 63% experienced breakthrough pain. In all, 69% reported pain-related difficulties with everyday activities; however, 50% believed that their quality of life was not considered a priority in their overall care by their health care professional. Conclusions: Across Europe and Israel, treatment of cancer pain is suboptimal. Pain and pain relief should be considered integral to the diagnosis and treatment of cancer; management guidelines should be revised to improve pain control in patients with cancer.
引用
收藏
页码:1420 / 1433
页数:14
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