Traditional Chinese Medicine Decoction Combined With Antipsychotic for Chronic Schizophrenia Treatment: A Systematic Review and Meta-analysis

被引:10
作者
Shi, Xiao-Jie [1 ]
Fan, Fang-Cheng [1 ]
Liu, Hua [1 ]
Ai, Yang-Wen [1 ]
Liu, Qing-Shan [1 ]
Jiao, Yu-Guo [1 ]
Cheng, Yong [1 ,2 ]
机构
[1] Minzu Univ China, Sch Pharm, Ctr Translat Neurosci, Key Lab Ethnomed,Minist Educ, Beijing, Peoples R China
[2] Minzu Univ China, Coll Life & Environm Sci, Beijing, Peoples R China
基金
中国国家自然科学基金; 北京市自然科学基金;
关键词
schizophrenia; TCM; antipsychotic; meta-analysis; adjuvant;
D O I
10.3389/fphar.2020.616088
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Despite several studies suggesting the effectiveness of traditional Chinese medicine (TCM) in schizophrenia, there is still a lack of systematic summary and analysis on the role of TCM as adjuvant therapy in chronic schizophrenia. For this purpose, we conducted a meta-analysis to study the efficacy of TCM as an adjuvant combined with antipsychotics in the treatment of chronic schizophrenia. Until April 2020, based on the review of six electronic databases, eight articles were selected. The articles compared TCM decoction assisted antipsychotic therapies with an antipsychotic alone in the treatment of chronic schizophrenia by analyzing a total of 810 cases. The results showed that TCM combined with antipsychotics have beneficial effects on the Positive and Negative Syndrome Scale (PANSS), including the changes in total score, negative score, and the clinical effects evaluated by the PANSS scale. Subgroup analysis showed that the effects of auxiliary TCM with different efficacy on the positive and psychopathological scores were significantly different. It was found that adjuvant treatment with TCM can reduce some side effects and improve the patient's living conditions in the evaluation of the Schizophrenia Quality Of Life Scale (SQLS). Many studies have proved that TCM is safe and well-tolerated. Although the difficulties of using limited TCM remains to be generalized, it still has great potential in the adjuvant treatment of chronic schizophrenia.
引用
收藏
页数:10
相关论文
共 50 条
[31]   Augmentation of Antipsychotic Treatment with Memantine in Patients with Schizophrenia: A Systematic Review and Meta-Analysis [J].
Vayisoglu, Sefa ;
Karahan, Sevilay ;
Anil Yagcioglu, A. Elif .
TURK PSIKIYATRI DERGISI, 2019, 30 (04) :253-259
[32]   Efficacy and safety of colonic dialysis combined with traditional Chinese medicine retention enema in the treatment of chronic renal failure A protocol for systematic review and meta-analysis [J].
Wang, Zhilei ;
Zhang, Shoulin ;
Zheng, Xue ;
Zhang, Lili .
MEDICINE, 2021, 100 (50) :E28082
[33]   Efficacy and safety of traditional Chinese herbal medicine combined with HAART in the treatment of HIV/AIDS A protocol for systematic review and meta-analysis [J].
Qian, Zhenzhen ;
Zhang, Yujin ;
Xie, Xiaoli ;
Wang, Junwen .
MEDICINE, 2021, 100 (52)
[34]   Acupuncture combined with traditional Chinese medicine preparation for the treatment of marrow suppression after chemotherapy A protocol for systematic review and meta-analysis [J].
Zhu, Qiongjie ;
Xu, Wenjin ;
Li, Xuesong .
MEDICINE, 2021, 100 (43) :E27646
[35]   Traditional Chinese Medicine for Diminished Ovarian Reserve: A Systematic Review and Meta-analysis [J].
Tian Xia ;
Ruihong Ma ;
Wei Mu ;
Mengdi Hu ;
Saihua Ma ;
Shuwen Mao ;
Yu Fu .
Chinese Herbal Medicines, 2014, (02) :93-102
[36]   Traditional Chinese Medicine for Alzheimer's Disease: A Systematic Review and Meta-Analysis [J].
Chen, Yuqing ;
Zhang, Danning ;
Chen, Teng ;
Zhao, Lixia ;
Wen, Lei ;
Hou, Ruihua .
AMERICAN JOURNAL OF CHINESE MEDICINE, 2025, 53 (01) :1-15
[37]   Oral traditional Chinese medicine for vestibular Migraine: A systematic review and meta-analysis [J].
Lu, Ying ;
Li, Jian ;
Xu, Hui ;
Wang, Chang-de .
JOURNAL OF CLINICAL NEUROSCIENCE, 2023, 110 :100-108
[38]   Traditional Chinese Medicine for Diminished Ovarian Reserve: A Systematic Review and Meta-analysis [J].
Xia, Tian ;
Ma, Rui-hong ;
Mu, Wei ;
Hu, Meng-di ;
Ma, Sai-hua ;
Mao, Shu-wen ;
Fu, Yu .
CHINESE HERBAL MEDICINES, 2014, 6 (02) :93-102
[39]   Traditional Chinese medicine for idiopathic membranous nephropathy: A systematic review and meta-analysis [J].
Shan, Wenjun ;
Guan, Haiyu ;
Gu, Haowen ;
Wang, Rongrong ;
Huang, Xiaoyan ;
Li, Ping ;
Xie, Ying ;
Bao, Kun ;
Qin, Xindong .
HELIYON, 2024, 10 (07)
[40]   Treatment of knee osteoarthritis with acupuncture combined with Chinese herbal medicine: a systematic review and meta-analysis [J].
Yang, Fan ;
Chen, Ying ;
Lu, Zhihui ;
Xie, Wanyi ;
Yan, Shan ;
Yang, Jiao ;
Li, Yunhai .
ANNALS OF PALLIATIVE MEDICINE, 2021, 10 (11) :11430-11444