Cellular plasticity of the pancreas

被引：9

作者：

Baeyens, Luc ^{[1
]}

Bouwens, Luc ^{[1
]}

机构：

[1] Vrije Univ Brussel, Cell Differentiat Unit, Diabet Res Ctr, B-1090 Brussels, Belgium

来源：

BIOLOGICAL CHEMISTRY | 2009年 / 390卷 / 10期

关键词：

beta-cells; cell reprogramming; metaplasia; pancreas; plasticity; transdifferentiation; INSULIN-SECRETING CELLS; EPIDERMAL-GROWTH-FACTOR; BETA-CELLS; ACINAR-CELLS; ADULT-RAT; PROGENITOR CELLS; MOLECULAR-BASIS; DUCT CELLS; IN-VIVO; DIFFERENTIATION;

D O I：

10.1515/BC.2009.117

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cell replacement therapy holds promises for treatment of patients suffering from diabetes mellitus. When determining the appropriate strategies to amplify the amount of transplantable beta-cells, sufficient knowledge of the developmental programs regulating beta-cell differentiation is crucial. Here, we describe the plasticity of the different pancreatic cell types in vivo and in vitro and their potential to serve as beta-cell progenitor.

引用

页码：995 / 1001

页数：7

共 50 条

[41] Cellular and population plasticity of helper CD4+ T cell responses
Magombedze, Gesham
Reddy, Pradeep B. J.
Eda, Shigetoshi
Ganusov, Vitaly V.
FRONTIERS IN PHYSIOLOGY, 2013, 4
[42] Cellular diversity of the somatosensory cortical map plasticity
Kole, Koen
Scheenen, Wim
Tiesinga, Paul
Celikel, Tansu
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2018, 84 : 100 - 115
[43] Cellular Plasticity in Breast Cancer Progression and Therapy
Kong, Deguang
Hughes, Connor J.
Ford, Heide L.
FRONTIERS IN MOLECULAR BIOSCIENCES, 2020, 7
[44] Extracellular Matrix and Cellular Plasticity in Musculoskeletal Development
Ma, Sophia Ka Yan
Chan, Andy Shing Fung
Rubab, Aqsa
Chan, Wilson Cheuk Wing
Chan, Danny
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
[45] Cellular organization and histogenesis of adenosquamous carcinoma of the pancreas: evidence supporting the squamous metaplasia concept
Boecker, Werner
Tiemann, Katharina
Boecker, Joerg
Toma, Marieta
Muders, Michael H.
Loening, Thomas
Buchwalow, Igor
Oldhafer, Karl J.
Neumann, Ulf
Feyerabend, Bernd
Fehr, Andre
Stenman, Goeran
HISTOCHEMISTRY AND CELL BIOLOGY, 2020, 154 (01) : 97 - 105
[46] Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development
Huang, Wei
Wang, Guangliang
Delaspre, Fabien
Vitery, Maria del Carmen
Beer, Rebecca L.
Parsons, Michael J.
DEVELOPMENTAL BIOLOGY, 2014, 394 (01) : 83 - 93
[47] Cellular Plasticity in Musculoskeletal Development, Regeneration, and Disease
Kaji, Deepak A.
Tan, Zhijia
Johnson, Gemma L.
Huang, Wesley
Vasquez, Kaetlin
Lehoczky, Jessica A.
Levi, Benjamin
Cheah, Kathryn S. E.
Huang, Alice H.
JOURNAL OF ORTHOPAEDIC RESEARCH, 2020, 38 (04) : 708 - 718
[48] Transdetermination: A New Trend in Cellular Reprogramming
Manohar, Rohan
Lagasse, Eric
MOLECULAR THERAPY, 2009, 17 (06) : 936 - 938
[49] Human pancreas development
Jennings, Rachel E.
Berry, Andrew A.
Strutt, James P.
Gerrard, David T.
Hanley, Neil A.
DEVELOPMENT, 2015, 142 (18): : 3126 - 3137
[50] Xenopus Pancreas Development
Pearl, Esther J.
Bilogan, Cassandra K.
Mukhi, Sandeep
Brown, Donald D.
Horb, Marko E.
DEVELOPMENTAL DYNAMICS, 2009, 238 (06) : 1271 - 1286

← 1 2 3 4 5 →