Lithium acetate-catalyzed Michael reaction between trimethylsilyl enolate and α,β-unsaturated carbonyl compound

被引：26
|
作者：
Nakagawa, T
Fujisawa, H
Yuzo, NI
Mukaiyama, T
机构：
[1] Kitasato Inst, Ctr Basic Res, Kita Ku, Tokyo 1140003, Japan
[2] Kitasato Univ, Inst Life Sci, Minato Ku, Tokyo 1088641, Japan
来源：
CHEMISTRY LETTERS | 2004年 / 33卷 / 08期
关键词：
D O I：
10.1246/cl.2004.1016
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Lithium acetate-catalyzed Michael reaction between trimethylsilyl enolates and alpha,beta-unsaturated carbonyl compounds in DMF proceeded smoothly to afford the corresponding Michael-adducts in good to high yields. Hindered alpha, beta-unsaturated ketones also behaved as an excellent Michael-acceptor in the above reaction at room temperature.
引用
收藏
页码：1016 / 1017
页数：2
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