Spatial hemodynamics, the endothelium, and focal atherogenesis - A cell cycle link?

被引:41
作者
Davies, PF
机构
[1] Univ Penn, Dept Pathol & Lab Med, Inst Med & Engn, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
关键词
hemodynamics; endothelium; cell cycle; atherosclerosis;
D O I
10.1161/01.RES.86.2.114
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:114 / 116
页数:3
相关论文
共 22 条
[1]   Laminar shear stress inhibits vascular endothelial cell proliferation by inducing cyclin-dependent kinase inhibitor p21Sdi1/Cip1/Waf1 [J].
Akimoto, S ;
Mitsumata, M ;
Sasaguri, T ;
Yoshida, Y .
CIRCULATION RESEARCH, 2000, 86 (02) :185-190
[2]   Protein kinase cδ inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27Kip1 [J].
Ashton, AW ;
Watanabe, G ;
Albanese, C ;
Harrington, EO ;
Ware, JA ;
Pestell, RG .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (30) :20805-20811
[3]   SUBCELLULAR-DISTRIBUTION OF SHEAR-STRESS AT THE SURFACE OF FLOW-ALIGNED AND NONALIGNED ENDOTHELIAL MONOLAYERS [J].
BARBEE, KA ;
MUNDEL, T ;
LAL, R ;
DAVIES, PF .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1995, 268 (04) :H1765-H1772
[4]   INCREASED ENDOTHELIAL CELL TURNOVER IN AREAS OF IN-VIVO EVANS-BLUE UPTAKE IN PIG AORTA [J].
CAPLAN, BA ;
SCHWARTZ, CJ .
ATHEROSCLEROSIS, 1973, 17 (03) :401-417
[5]  
CORNHILL JF, 1990, MG ATHEROSC, V15, P13
[6]   A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis [J].
Davies, PF ;
Polacek, DC ;
Handen, JS ;
Helmke, BP ;
DePaola, N .
TRENDS IN BIOTECHNOLOGY, 1999, 17 (09) :347-351
[7]   FLOW-MEDIATED ENDOTHELIAL MECHANOTRANSDUCTION [J].
DAVIES, PF .
PHYSIOLOGICAL REVIEWS, 1995, 75 (03) :519-560
[8]  
DAVIES PF, 1986, P NATL ACAD SCI USA, V83, P2114, DOI 10.1073/pnas.83.7.2114
[9]   Mechanism for heterogeneous endothelial responses to flow in vivo and in vitro [J].
Davies, PF ;
Mundel, T ;
Barbee, KA .
JOURNAL OF BIOMECHANICS, 1995, 28 (12) :1553-1560
[10]  
DEPAOLA N, 1993, ARTERIOSCLER THROMB, V13, P465