Rhodium-catalyzed enantioselective conjugate silyl transfer: 1,4-addition of silyl boronic esters to cyclic enones and lactones

被引：104

作者：

Walter, Christian ^{[1
]}

Auer, Gertrud ^{[1
]}

Oestreich, Martin ^{[1
]}

机构：

[1] Univ Freiburg, Inst Organ Chem & Biochem, D-79104 Freiburg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 34期

关键词：

asymmetric catalysis; boron; homogeneous catalysis; rhodium; silicon;

D O I：

10.1002/anie.200601747

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Missing linkage: A chiral cationic rhodium complex catalyzes the enantioselective conjugate addition of silyl anion equivalents to cyclic α,β-unsaturated ketones (X = CH2) and esters (X = O; see scheme). This unprecedented catalytic process enables the asymmetric formation of a carbon-silicon bond, thus providing a facile access to α-chiral organosilicon compounds. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5675 / 5677

页数：3

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