Roseosporol A, the first isolation of a novel sesquiterpenoid from Streptomyces roseosporus

被引:5
作者
Deng, Lina [1 ]
Wang, Rui [1 ]
Wang, Guowei [1 ]
Liu, Mingxu [1 ]
Liao, Zhihua [2 ]
Liao, Guojian [1 ]
Chen, Min [1 ]
机构
[1] Southwest Univ, Minist Educ, Key Lab Luminescent & Real Time Analyt Chem, Coll Pharmaceut Sci, Chongqing, Peoples R China
[2] Southwest Univ, Sch Life Sci, Chongqing, Peoples R China
关键词
Roseosporol A; sesquiterpenoid; Lsr2-deletion; Streptomyces roseosporus; METABOLITES; DIKETOPIPERAZINES;
D O I
10.1080/14786419.2018.1484457
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A novel sesquiterpenoid, roseosporol A (1), together with 12 known compounds (2-13) were isolated from the ethyl acetate extract of Lsr2-deletion mutant strain of Streptomyces roseosporus. Their structures were determined by spectroscopic methods, including NMR, HRMS, UV, IR and ECD. [GRAPHICS] .
引用
收藏
页码:2038 / 2043
页数:6
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