New ent-abietanoids from Isodon rubescens

被引：21

作者：

Han, QB

Li, RT

Zhang, JX

Sun, HD ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Xinxiang Med Coll, Dept Chem, Xinxiang 453000, Henan, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2004年 / 87卷 / 04期

关键词：

D O I：

10.1002/hlca.200490072

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Six new ent-abietane diterpenoids, rubescensins I-M (1-5) and P (6), along with two related acetonide derivatives (7 and 8), were isolated from Isodon rubescens. Their structures were elucidated by detailed spectroscopic analysis. Compound 5 is the first N-containing diterpenoid from the genus Isodon, exhibiting notable cytotoxicity against human tumor K562 cells.

引用

页码：1007 / 1015

页数：9

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