Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines

被引：337
作者：
Zani, Lorenzo [1 ]
Bolm, Carsten [1 ]
机构：
[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 41期
关键词：
D O I：
10.1039/b607986p
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic amines via the direct addition of alkynes to imines and related carbon - nitrogen electrophiles in the presence of metal catalysts or promoters.
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页码：4263 / 4275
页数：13
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