Fully integrated photoacoustic microscopy and photoplethysmography of human in vivo

被引：36

作者：

Ahn, Joongho ^{[1
,2
,3
,4
]}

Baik, Jin Woo ^{[1
,2
,3
,4
]}

Kim, Yeonggeon ^{[1
,2
,3
,4
]}

Choi, Karam ^{[5
]}

Park, Jeongwoo ^{[1
,2
,3
,4
]}

Kim, Hyojin ^{[1
,2
,3
,4
]}

Kim, Jin Young ^{[1
,2
,3
,4
]}

Kim, Hyung Ham ^{[1
,2
,3
,4
]}

Nam, Sung Hyun ^{[5
]}

Kim, Chulhong ^{[1
,2
,3
,4
]}

机构：

[1] Pohang Univ Sci & Technol, Sch Interdisciplinary Biosci & Bioengn, Dept Elect Engn, Pohang Si 37673, Gyeongsangbuk D, South Korea

[2] Pohang Univ Sci & Technol, Sch Interdisciplinary Biosci & Bioengn, Dept Convergence IT Engn, Pohang Si 37673, Gyeongsangbuk D, South Korea

[3] Pohang Univ Sci & Technol, Sch Interdisciplinary Biosci & Bioengn, Dept Mech Engn, Pohang Si 37673, Gyeongsangbuk D, South Korea

[4] Pohang Univ Sci & Technol, Med Device Innovat Ctr, Pohang Si 37673, Gyeongsangbuk D, South Korea

[5] Samsung Elect Co Ltd, Samsung Adv Inst Technol, Suwon 16678, Gyeonggi Do, South Korea

来源：

PHOTOACOUSTICS | 2022年 / 27卷

基金：

新加坡国家研究基金会;

关键词：

Blood vessel; Vascular movement; Blood volume change; Pulsation; Heartbeat; TOMOGRAPHY;

D O I：

10.1016/j.pacs.2022.100374

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Photoacoustic microscopy (PAM) is used to visualize blood vessels and to monitor their time-dependent changes. Photoplethysmography (PPG) measures hemodynamic time-series changes such as heart rate. However, PPG's limited visual access to the dynamic changes of blood vessels has prohibited further understanding of hemodynamics. Here, we propose a novel, fully integrated PAM and photoplethysmography (PAM-PPG) system to understand hemodynamic features in detail. Using the PAM-PPG system, we simultaneously acquire vascular images (by PAM) and changes in the blood volume (by PPG) from human fingers. Next, we determine the heart rate from changes in the PA signals, which match well with the PPG signals. These changes can be measured if the blood flow is not blocked. From the results, we believe that PAM-PPG could be a useful clinical tool in various clinical fields such as cardiology and endocrinology.

引用

页数：7

共 44 条

[1] High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers [J].