Synthesis of novel spiropyrrolidine/pyrrolizine-oxindole scaffolds through 1,3-dipolar cycloadditions

被引：50
|
作者：
Ghandi, Mehdi [1 ]
Yari, Ahmad [1 ]
Rezaei, Seyed Jamal Tabatabaei [1 ]
Taheri, Abuzar [1 ]
机构：
[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 33期
关键词：
Sarcosine; Azomethine ylide; Spirooxindole; Cycloaddition; ONE-POT SYNTHESIS; AZOMETHINE YLIDES; INHIBITORS;
D O I：
10.1016/j.tetlet.2009.06.033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot, three-component condensation of sarcosine or proline Schiff bases with several aromatic alclehydes and the Knoevenagel adduct of isatin-malononitrile successfully affords spiropyrrolidine-oxindoles and spiropyrrolizine-oxindoles. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4724 / 4726
页数：3
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