Synthesis of novel spiropyrrolidine/pyrrolizine-oxindole scaffolds through 1,3-dipolar cycloadditions

被引：50
|
作者：
Ghandi, Mehdi [1 ]
Yari, Ahmad [1 ]
Rezaei, Seyed Jamal Tabatabaei [1 ]
Taheri, Abuzar [1 ]
机构：
[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 33期
关键词：
Sarcosine; Azomethine ylide; Spirooxindole; Cycloaddition; ONE-POT SYNTHESIS; AZOMETHINE YLIDES; INHIBITORS;
D O I：
10.1016/j.tetlet.2009.06.033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot, three-component condensation of sarcosine or proline Schiff bases with several aromatic alclehydes and the Knoevenagel adduct of isatin-malononitrile successfully affords spiropyrrolidine-oxindoles and spiropyrrolizine-oxindoles. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4724 / 4726
页数：3
相关论文
共 50 条
  • [31] Asymmetric 1,3-dipolar cycloadditions of acrylamides
    Kissane, Marie
    Maguire, Anita R.
    CHEMICAL SOCIETY REVIEWS, 2010, 39 (02) : 845 - 883
  • [32] SOME 1,3-DIPOLAR CYCLOADDITIONS TO METHOXYBUTENYNES
    NOEL, M
    VOQUANG, Y
    VOQUANG, L
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1970, 270 (01): : 80 - &
  • [33] ON MECHANISM OF 1,3-DIPOLAR CYCLOADDITIONS . AREPLY
    HUISGEN, R
    JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (06): : 2291 - &
  • [34] 1,3-Dipolar cycloadditions of azomethine imines
    Najera, Carmen
    Sansano, Jose M.
    Yus, Miguel
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 13 (32) : 8596 - 8636
  • [35] Stereoselective intramolecular 1,3-dipolar cycloadditions
    Namboothiri, INN
    Hassner, A
    STEREOSELECTIVE HETEROCYCLIC SYNTHESIS III, 2001, 216 : 1 - 49
  • [36] CENTENARY LECTURE - 1,3-DIPOLAR CYCLOADDITIONS
    HUISGEN, R
    PROCEEDINGS OF THE CHEMICAL SOCIETY OF LONDON, 1961, (OCT): : 357 - &
  • [37] Understanding the 1,3-Dipolar Cycloadditions of Allenes
    Yu, Song
    Vermeeren, Pascal
    van Dommelen, Kevin
    Bickelhaupt, F. Matthias
    Hamlin, Trevor A.
    CHEMISTRY-A EUROPEAN JOURNAL, 2020, 26 (50) : 11529 - 11539
  • [38] 1,3-DIPOLAR CYCLOADDITIONS OF FULMINIC ACID
    HUISGEN, R
    CHRISTL, M
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1967, 6 (05) : 456 - &
  • [39] 1,3-dipolar cycloadditions in aqueous media
    Molteni, Giorgio
    HETEROCYCLES, 2006, 68 (10) : 2177 - +
  • [40] Regioselective synthesis of spiropyrrolidine/spiropyrrolizidine/spirothiazolidine-grafted macrocycles through 1,3-dipolar cycloaddition methodology
    Purushothaman, S.
    Prasanna, R.
    Raghunathan, R.
    TETRAHEDRON, 2013, 69 (46) : 9742 - 9750
12345