Metabolic Syndrome in Post-Pulmonary Tuberculosis-Associated Obstructive Airway Disease: A Cross-Sectional Analytical Study

被引:2
作者
Shahana, M. P. [1 ]
Mohapatra, Madhusmita Mohanty [1 ]
Babu, Vemuri Mahesh [1 ]
Rajaram, Manju [1 ]
Rajaa, Sathish [2 ,3 ]
Periyasamy, Senthil Kumar Gandhipuram [4 ]
机构
[1] Jawaharlal Inst Postgrad Med Educ & Res, Pulm Med, Pondicherry, India
[2] Employees State Insurance Corp Med Coll, Community Med, Chennai, Tamil Nadu, India
[3] Post Grad Inst Med Sci & Res, Chennai, Tamil Nadu, India
[4] Jawaharlal Inst Postgrad Med Educ & Res, Biochem, Pondicherry, India
关键词
tuberculosis-associated obstructive airway disease; endocrinology and diabetes; waist circumference; tuberculosis; metabolic syndrome; SYSTEMIC INFLAMMATION; PREVALENCE; PROFILE;
D O I
10.7759/cureus.23640
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background The aim of this study is to assess the prevalence of metabolic syndrome in tuberculosis-associated obstructive airway disease (TOPD) patients, as well as the association of its components with the severity of airflow obstruction. Methodology In this cross-sectional analytical study, we evaluated the clinical profile, spirometry, waist circumference, blood pressure, lipid profile, fasting plasma glucose, and the association of each component with the severity of airflow obstruction. Results The prevalence of metabolic syndrome in TOPD was found to be was 25.77% (95% confidence interval = 18.11-35.28) among study participants. Reduced high-density lipoprotein was the deranged component and was associated with increased severity in Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II compared to GOLD stage IV. Conclusions The prevalence of metabolic syndrome in TOPD has a severe impact on patients' treatment, outcomes, and complications. However, in our study, tuberculosis-associated metabolic syndrome was the same as the general population. Low high-density lipoprotein levels were associated with the severity of the airflow obstruction.
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页数:9
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