Beyond cochlear implants: awakening the deafened brain

被引：176

作者：

Moore, David R. ^{[1
,2
]}

Shannon, Robert V. ^{[3
]}

机构：

[1] MRC, Inst Hearing Res, Nottingham, England

[2] Natl Biomed Res Unit Hearing, Nottingham, England

[3] House Ear Res Inst, Los Angeles, CA USA

来源：

NATURE NEUROSCIENCE | 2009年 / 12卷 / 06期

基金：

英国医学研究理事会;

关键词：

PRIMARY AUDITORY-CORTEX; ELECTRICAL-STIMULATION; STEM IMPLANT; SPEECH RECOGNITION; DISTORTED SPEECH; CRITICAL PERIOD; CHILDREN; HEARING; PERFORMANCE; PERCEPTION;

D O I：

10.1038/nn.2326

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cochlear implants have provided hearing to more than 120,000 deaf people. Recent surgical developments include direct electrical stimulation of the brain, bilateral implants and implantation in children less than 1 year old. However, research is beginning to refocus on the role of the brain in providing benefits to implant users. The auditory system is able to use the highly impoverished input provided by implants to interpret speech, but this only works well in those who have developed language before their deafness or in those who receive their implant at a very young age. We discuss recent evidence suggesting that developing the ability of the brain to learn how to use an implant may be as important as further improvements of the implant technology.

引用

页码：686 / 691

页数：6

共 51 条

[1] Quiet as a mouse: dissecting the molecular and genetic basis of hearing [J].

Brown, Steve D. M. ;

Hardisty-Hughes, Rachel E. ;

Mburu, Philomena .

NATURE REVIEWS GENETICS, 2008, 9 (04) :277-290

[2] Open set speech perception with auditory brainstem implant? [J].

Colletti, V ;

Shannon, RV .

LARYNGOSCOPE, 2005, 115 (11) :1974-1978

[3] The first successful case of hearing produced by electrical stimulation of the human midbrain [J].

Colletti, Vittorio ;

Shannon, Robert ;

Carner, Marco ;

Sacchetto, Luca ;

Turazzi, Sergio ;

Masotto, Barbara ;

Colletti, Lilliana .

OTOLOGY & NEUROTOLOGY, 2007, 28 (01) :39-43

[4] Learning to hear: plasticity of auditory cortical processing [J].

Dahmen, Johannes C. ;

King, Andrew J. .

CURRENT OPINION IN NEUROBIOLOGY, 2007, 17 (04) :456-464

[5] Lexical information drives; Perceptual learning of distorted speech: Evidence from the comprehension of noise-vocoded sentences [J].

Davis, MH ;

Johnsrude, IS ;

Hervais-Adelman, A ;

Taylor, K ;

McGettigan, C .

JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL, 2005, 134 (02) :222-241

[6] Critical period window for spectral tuning defined in the primary auditory cortex (A1) in the rat [J].

de Villers-Sidani, Etienne ;

Chang, Edward F. ;

Bao, Shaowen ;

Merzenich, Michael M. .

JOURNAL OF NEUROSCIENCE, 2007, 27 (01) :180-189

[7] Role of Auditory Cortex in Noise- and Drug-Induced Tinnitus [J].

Eggermont, Jos J. .

AMERICAN JOURNAL OF AUDIOLOGY, 2008, 17 (02) :S162-S169

[8] Djourno, Eyries, and the first implanted electrical neural stimulator to restore hearing [J].

Eisen, MD .

OTOLOGY & NEUROTOLOGY, 2003, 24 (03) :500-506

[9] Speech recognition with reduced spectral cues as a function of age [J].

Eisenberg, LS ;

Shannon, RV ;

Martinez, AS ;

Wygonski, J ;

Boothroyd, A .

JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2000, 107 (05) :2704-2710

[10] Cochlear Implant Use Following Neonatal Deafness Influences the Cochleotopic Organization of the Primary Auditory Cortex in Cats [J].

Fallon, James B. ;

Irvine, Dexter R. F. ;

Shepherd, Robert K. .

JOURNAL OF COMPARATIVE NEUROLOGY, 2009, 512 (01) :101-114

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