ABO blood group and von Willebrand factor: biological implications

被引：45
作者：
Franchini, Massimo [1 ]
Crestani, Silvia [1 ]
Frattini, Francesco [1 ]
Sissa, Cinzia [1 ]
Bonfanti, Carlo [1 ]
机构：
[1] Azienda Osped Carlo Poma, Dipartimento Med Trasfus & Ematol, Mantua, Italy
来源：
CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2014年 / 52卷 / 09期
关键词：
ABO; ADAMTS13; desmopressin; LRP1; von Willebrand disease; von Willebrand factor; N-LINKED GLYCOSYLATION; GENETIC RISK-FACTOR; FACTOR-VIII; ADAMTS13; PROTEOLYSIS; VASCULAR-DISEASE; HALF-LIFE; IN-VIVO; CLEARANCE; PHENOTYPE; COHORT;
D O I：
10.1515/cclm-2014-0564
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
ABO blood group antigens are complex carbohydrate molecules expressed on the surface of red blood cells and a variety of human cells and tissues. It is well known that ABO blood type exerts a profound influence on hemostasis, being a major determinant of von Willebrand factor (VWF), and consequently factor VIII, plasma levels. In this review, we will focus on the molecular mechanisms underlying the interaction between ABO blood group and VWF in normal and pathological conditions.
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收藏
页码：1273 / 1276
页数：4
相关论文
共 37 条
  • [1] The relationship between blood groups and disease
    Anstee, David. J.
    [J]. BLOOD, 2010, 115 (23) : 4635 - 4643
  • [2] An influence of ABO blood group on the rate of proteolysis of von Willebrand factor by ADAMTS13
    Bowen, DJ
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2003, 1 (01) : 33 - 40
  • [3] Clearance of von Willebrand factor
    Casari, C.
    Lenting, P. J.
    Wohner, N.
    Christophe, O. D.
    Denis, C. V.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 : 202 - 211
  • [4] CASTAMAN G, 1995, THROMB HAEMOSTASIS, V73, P551
  • [5] Blood group significantly influences von Willebrand factor increase and half-life after desmopressin in von Willebrand disease Vicenza
    Castaman, G.
    Tosetto, A.
    Eikenboom, J. C.
    Rodeghiero, F.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2010, 8 (09) : 2078 - 2080
  • [6] ABO blood group also influences the von Willebrand factor (VWF) antigen level in heterozygous carriers of VWF null alleles, type 2N mutation Arg854GIn, and the missense mutation Cys2362Phe
    Castaman, G
    Eikenboom, JCJ
    [J]. BLOOD, 2002, 100 (05) : 1927 - 1928
  • [7] Davies JA, 2008, J THROMB HAEMOST, V6, P97
  • [8] Effect of von Willebrand factor Y/C1584 on in vivo protein level and function and interaction with ABO blood group
    Davies, James Anthony
    Collins, Peter William
    Hathaway, Lee Sarah
    Bowen, Derrick John
    [J]. BLOOD, 2007, 109 (07) : 2840 - 2846
  • [9] ABO Blood Group and Vascular Disease: An Update
    Dentali, Francesco
    Sironi, Anna Paola
    Ageno, Walter
    Crestani, Silvia
    Franchini, Massimo
    [J]. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2014, 40 (01) : 49 - 59
  • [10] Non-O Blood Type Is the Commonest Genetic Risk Factor for VTE: Results from a Meta-Analysis of the Literature
    Dentali, Francesco
    Sironi, Anna Paola
    Ageno, Walter
    Turato, Sara
    Bonfanti, Carlo
    Frattini, Francesco
    Crestani, Silvia
    Franchini, Massimo
    [J]. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2012, 38 (05) : 535 - 547
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