Perineural Invasion in Cutaneous Squamous Cell Carcinoma

被引:18
作者
Perez Garcia, M. P. [1 ]
Mateu Puchades, A. [2 ]
Sanmartin Jimenez, O. [3 ]
机构
[1] Hosp Marina Salud, Serv Dermatol, Alicante, Spain
[2] Hosp Dr Peset, Serv Dermatol, Valencia, Spain
[3] Inst Valenciano Oncol, Serv Dermatol, Valencia, Spain
来源
ACTAS DERMO-SIFILIOGRAFICAS | 2019年 / 110卷 / 06期
关键词
Squamous cell carcinoma; Perineural infiltration; High risk; Radiotherapy; MOHS MICROGRAPHIC SURGERY; SKIN-CANCER; RADIOGRAPHIC FINDINGS; BASAL-CELL; HEAD; SPREAD; NECK; PROGNOSIS; IMPACT; IDENTIFICATION;
D O I
10.1016/j.ad.2018.10.006
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cutaneous squamous cell carcinoma is sometimes characterized by an increased risk of locoregional recurrence and occasionally distant metastasis. Several clinical and pathological factors, including perineural invasion, have been shown to have prognostic value in this setting. Perineural invasion, that is, the spread of tumor cells into the space surrounding a nerve, is usually an incidental finding. In the presence of symptoms or radiographic evidence of perineural spread, the diagnosis is clinical perineural invasion, which is associated with an increased risk of local recurrence and mortality. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:426 / 433
页数:8
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