Amino acid-based surfactants: New antimicrobial agents

被引:157
作者
Pinazo, A. [1 ]
Manresa, M. A. [2 ]
Marques, A. M. [2 ]
Bustelo, M. [1 ]
Espuny, M. J. [2 ]
Perez, L. [1 ]
机构
[1] CSIC, Dept Chem & Surfactant Technol, IQAC, C JordiGirona 18-26, Barcelona 08034, Spain
[2] Univ Barcelona, Fac Farm, Dept Microbiol, Ave Joan 13 S-N, E-08028 Barcelona, Spain
关键词
Amino acid-based surfactants; Antimicrobial activity; Mode of action; Aggregation; Cytotoxicity; CATIONIC AMPHIPHILIC COMPOUNDS; ARGININE-BASED SURFACTANTS; ANTIBACTERIAL ACTIVITY; BIOLOGICAL-PROPERTIES; GEMINI SURFACTANTS; STAPHYLOCOCCUS-AUREUS; ENZYMATIC-SYNTHESIS; ACTIVE PROPERTIES; L-LYSINE; LIPOPEPTIDES;
D O I
10.1016/j.cis.2015.11.007
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:17 / 39
页数:23
相关论文
共 110 条
[21]   Cation-pi interactions in chemistry and biology: A new view of benzene, Phe, Tyr, and Trp [J].
Dougherty, DA .
SCIENCE, 1996, 271 (5246) :163-168
[22]   Counterion-Induced Modulation in the Antimicrobial Activity and Biocompatibility of Amphiphilic Hydrogelators: Influence of in-Situ-Synthesized Ag-Nanoparticle on the Bactericidal Property [J].
Dutta, Sounak ;
Shome, Anshupriya ;
Kar, Tanmoy ;
Das, Prasanta Kumar .
LANGMUIR, 2011, 27 (08) :5000-5008
[23]  
Epand RM, 1997, BIOPOLYMERS, V43, P15, DOI 10.1002/(SICI)1097-0282(1997)43:1<15::AID-BIP3>3.3.CO
[24]  
2-T
[25]   Surface tensiometric study of multiple complexation and hemolysis by mixed surfactants and cyclodextrins [J].
Funasaki, N ;
Ohigashi, M ;
Hada, S ;
Neya, S .
LANGMUIR, 2000, 16 (02) :383-388
[26]  
Garcia MT, 2003, ENVIRON POLLUT, V111, P169
[27]  
Geiger R, 1981, PEPTIDES, V3
[28]  
Gibson H, 1995, PRESERVATION SURFACT
[29]   Antimicrobial peptides: an overview of a promising class of therapeutics [J].
Giuliani, Andrea ;
Pirri, Giovanna ;
Nicoletto, Silvia Fabiole .
CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 2007, 2 (01) :1-33
[30]   Molecular-thermodynamic theory of micellization of pH-sensitive surfactants [J].
Goldsipe, A ;
Blankschtein, D .
LANGMUIR, 2006, 22 (08) :3547-3559