Silica gel/FeCl3:: An efficient and recyclable heterogenous catalyst for one step synthesis of 4(3H)-quinazolinones under solvent free conditions

被引：54
作者：
Chari, M. Adharvana [1 ]
Shobha, D. [1 ]
Mukkanti, K. [1 ]
机构：
[1] JNT Univ, Inst Sci & Technol, AG Soc, Dept Chem,Catalysis Lab, Hyderabad 500072, Andhra Pradesh, India
来源：
CATALYSIS COMMUNICATIONS | 2006年 / 7卷 / 10期
关键词：
silica gel supported ferric chloride; solvent free conditions; 4(3H)-quinazolinones;
D O I：
10.1016/j.catcom.2006.02.026
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Silica gel supported ferric chloride catalyzes efficiently the three component coupling reaction of anthranilic acid, ortho esters and amines under solvent free conditions to afford the corresponding 4(3H)-quinazolinones in single step. This new approach consistently has the advantage of excellent yields (84-98%) and short reaction times of 5-10 min. The catalyst can be recovered and recycled. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：787 / 790
页数：4
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