The Effect of Morphology on the Biodegradation Behavior of Porous Magnesium Bone Scaffold

被引：2

作者：

Basri, Hasan ^{[1
]}

Syahrom, Ardiansyah ^{[2
,3
]}

Saad, Amir Putra Md ^{[2
,3
]}

Adibah, Rabiatul A. R. ^{[2
,3
]}

Prakoso, Akbar Teguh ^{[1
]}

Diansyah, Apreka ^{[1
]}

Putra, Risky Utama ^{[1
]}

机构：

[1] Univ Sriwijaya, Fac Engn, Dept Mech Engn, Inderalaya 30622, Kabupaten Ogan, Indonesia

[2] Univ Teknol Malaysia, Fac Mech Engn, Dept Appl Mech & Design, Sekudai 81310, Johor, Malaysia

[3] Univ Teknol Malaysia, IHCE, SITC, Sekudai 81310, Johor, Malaysia

来源：

1ST SRIWIJAYA INTERNATIONAL CONFERENCE ON ENVIRONMENTAL ISSUES 2018 (1ST SRICOENV 2018) | 2018年 / 68卷

关键词：

PERMEABILITY;

D O I：

10.1051/e3sconf/20186801020

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The purpose of this study is to analyze the influence of morphology on the degrading behavior of porous magnesium bone scaffold by using computer simulation. Based on the experimental work, the three bone scaffold prepared with 30%, 41%, and 55% of porosity, respectively. The bone scaffold made of pure magnesium that immersed in simulated body fluid (SBF) for 72 hours with constant flow rates of 0.025 ml/min. After degradation, each specimen was scanned by mu CT with a resolution of 17 mu m. In this study, three different morphology before and after degradation was performed by computer simulation using the FSI method. Each specimen before and after degradation were given different bone strain (1000-3500 mu strain) that create displacement variations on the bone scaffold. Before degradation, the outcomes showed that the variation of displacement affects fluid characteristic change and for the specimen C (55% of porosity) generates the highest permeability with the value of 8.78 x 10(-10) m(2). After degradation, specimen A (30% of porosity) has a higher average shear stress of 2.04 x 10(-3) Pa, specimen C (55% of porosity) has degradation rate of 3.37 mg/cm(2)/d and the highest porosity of 75.81%.

引用

页数：9