A Review of Recent Advancement in Integrating Omics Data with Literature Mining towards Biomedical Discoveries

被引:28
作者
Raja, Kalpana [1 ]
Patrick, Matthew [1 ]
Gao, Yilin [1 ]
Madu, Desmond [1 ]
Yang, Yuyang [1 ]
Tsoi, Lam C. [1 ,2 ,3 ]
机构
[1] Univ Michigan, Sch Med, Dept Dermatol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Sch Med, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA
基金
新加坡国家研究基金会;
关键词
PRECISION MEDICINE; MOLECULAR-BIOLOGY; SYSTEMS BIOLOGY; TEXT; INFORMATION; DISEASE; IDENTIFICATION; TRANSCRIPTOMICS; TECHNOLOGIES; METABOLOMICS;
D O I
10.1155/2017/6213474
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the past decade, the volume of "omics" data generated by the different high-throughput technologies has expanded exponentially. The managing, storing, and analyzing of this big data have been a great challenge for the researchers, especially when moving towards the goal of generating testable data-driven hypotheses, which has been the promise of the high-throughput experimental techniques. Different bioinformatics approaches have been developed to streamline the downstream analyzes by providing independent information to interpret and provide biological inference. Text mining (also known as literature mining) is one of the commonly used approaches for automated generation of biological knowledge from the huge number of published articles. In this review paper, we discuss the recent advancement in approaches that integrate results from omics data and information generated from text mining approaches to uncover novel biomedical information.
引用
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页数:10
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