Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization

被引：26

作者：

Liang, Fushun ^{[1
]}

Cheng, Xin ^{[1
]}

Liu, Jing ^{[1
]}

Liu, Qun ^{[1
]}

机构：

[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 24期

关键词：

ANNULATION STRATEGY; DERIVATIVES; CHEMISTRY; DIHYDROFURANS; REARRANGEMENT; ENONES;

D O I：

10.1039/b905742k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.

引用

页码：3636 / 3638

页数：3

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