Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization

被引：26
|
作者：
Liang, Fushun [1 ]
Cheng, Xin [1 ]
Liu, Jing [1 ]
Liu, Qun [1 ]
机构：
[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2009年 / 24期
关键词：
ANNULATION STRATEGY; DERIVATIVES; CHEMISTRY; DIHYDROFURANS; REARRANGEMENT; ENONES;
D O I：
10.1039/b905742k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.
引用
收藏
页码：3636 / 3638
页数：3
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