A tandem synthesis of 3-aroylcoumarinoflavones catalyzed by L-proline and their antioxidant activity

被引：2

作者：

Thirupathi, G. ^{[1
]}

Goud, E. Yadaiah ^{[1
]}

Hemasri, Y. ^{[3
]}

Ali, MD. Suban ^{[4
]}

Rao, Y. Jayaprakash ^{[1
,2
]}

机构：

[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India

[2] Telangana Univ, Dept Chem, Nizamabad 503322, India

[3] Osmania Univ, Dept Chem, Nizam Coll, Hyderabad 500001, Andhra Pradesh, India

[4] Sri Venkateswara Univ, Dept Biochem, Tirupati 517502, Andhra Pradesh, India

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2017年 / 14卷 / 02期

关键词：

7-Hydroxyflavones; Duff reaction; Knoevenagel condensation; Antioxidant activity; IN-VITRO; CONDENSATION; FLAVONOIDS; CHEMISTRY; COUMARINS; KETONES;

D O I：

10.1007/s13738-016-0995-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile, convenient, efficient and high-yielding synthesis of 3-aroylcoumarinoflavones has been developed by the condensation of easily synthesized 7-hydroxy-8-formylflavones and benzoyl acetonitriles in the presence of catalytic amount of l-proline in ethanol reflux. All the synthesized compounds were evaluated for their antioxidant activity. Some of the compounds showed very good activity compared to standard BHT.

引用

页码：477 / 483

页数：7

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