A tandem synthesis of 3-aroylcoumarinoflavones catalyzed by L-proline and their antioxidant activity

被引：2
|
作者：
Thirupathi, G. [1 ]
Goud, E. Yadaiah [1 ]
Hemasri, Y. [3 ]
Ali, MD. Suban [4 ]
Rao, Y. Jayaprakash [1 ,2 ]
机构：
[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India
[2] Telangana Univ, Dept Chem, Nizamabad 503322, India
[3] Osmania Univ, Dept Chem, Nizam Coll, Hyderabad 500001, Andhra Pradesh, India
[4] Sri Venkateswara Univ, Dept Biochem, Tirupati 517502, Andhra Pradesh, India
来源：
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2017年 / 14卷 / 02期
关键词：
7-Hydroxyflavones; Duff reaction; Knoevenagel condensation; Antioxidant activity; IN-VITRO; CONDENSATION; FLAVONOIDS; CHEMISTRY; COUMARINS; KETONES;
D O I：
10.1007/s13738-016-0995-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile, convenient, efficient and high-yielding synthesis of 3-aroylcoumarinoflavones has been developed by the condensation of easily synthesized 7-hydroxy-8-formylflavones and benzoyl acetonitriles in the presence of catalytic amount of l-proline in ethanol reflux. All the synthesized compounds were evaluated for their antioxidant activity. Some of the compounds showed very good activity compared to standard BHT.
引用
收藏
页码：477 / 483
页数：7
相关论文
共 50 条
  • [1] A tandem synthesis of 3-aroylcoumarinoflavones catalyzed by l-proline and their antioxidant activity
    G. Thirupathi
    E. Yadaiah Goud
    Y. Hemasri
    MD. Suban Ali
    Y. Jayaprakash Rao
    Journal of the Iranian Chemical Society, 2017, 14 : 477 - 483
  • [2] Multicomponent synthesis of dihydropyridines catalyzed by L-proline
    Zare, Leila
    Nikpassand, Mohammad
    CHINESE CHEMICAL LETTERS, 2011, 22 (05) : 531 - 534
  • [3] L-Proline catalyzed condensation-cyclization tandem process: Facile and effective synthesis of 3-polyfluoroalkanesulfonyl coumarin
    Han, Jianwei
    Xin, Yong
    Zhao, Jingwei
    Zhu, Shizheng
    JOURNAL OF FLUORINE CHEMISTRY, 2011, 132 (06) : 409 - 413
  • [4] L-Proline Catalyzed Synthesis of Steroidal Pyridones And Their DFT Studies
    Iqbal, Arfeen
    Khan, Asna
    Alam, Mohammad Jane
    Siddiqui, Tabassum
    Ali, Abad
    CHEMISTRYSELECT, 2022, 7 (43):
  • [5] A Facile, Chemoselective and Eco-friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline
    Bhupathi, Raja S.
    Devi, B. Rama
    Dubey, P. K.
    ASIAN JOURNAL OF CHEMISTRY, 2011, 23 (12) : 5521 - 5524
  • [6] An Efficient One-Pot Synthesis of Pyrazolo[3,4-b]pyridinone Derivatives Catalyzed by L-Proline
    Shi, Chun-Ling
    Chen, Hui
    Shi, Da-Qing
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 48 (02) : 351 - 354
  • [7] L-proline catalyzed one-pot synthesis of benzoxanthenes in aqueous medium
    Ahmed, Kajol
    Karmaker, Pran Gopal
    Roy, Harendra N.
    SYNTHETIC COMMUNICATIONS, 2024, 54 (20) : 1736 - 1747
  • [8] Asymmetric Michael Reaction Catalyzed by Proline Lithium Salt: Efficient Synthesis of L-Proline and Isoindoloisoquinolinone Derivatives
    Xu, Kun
    Zhang, Sheng
    Hu, Yanbin
    Zha, Zhenggen
    Wang, Zhiyong
    CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (11) : 3573 - 3578
  • [9] L-proline catalyzed solvent-free Knoevenagel condensation for the synthesis of 3-substituted coumarins
    Karade, Nandkishor N.
    Gampawar, Sumit V.
    Shinde, Sandeep V.
    Jadhav, Wamanrao N.
    CHINESE JOURNAL OF CHEMISTRY, 2007, 25 (11) : 1686 - 1689
  • [10] Asymmetric synthesis of a 3,4-substituted pyrrolidine by L-proline catalyzed direct enolexo aldolization
    Kumar, Indresh
    Bhide, S. R.
    Rode, C. V.
    TETRAHEDRON-ASYMMETRY, 2007, 18 (10) : 1210 - 1216
12345