An efficient solvent-tuning approach for the rapid synthesis of thiazolidinone derivatives and the selective synthesis of 2-amino-4H-1,3-thiazin-4-one and dimethyl 3,3′-thiodiacrylates

被引：21

作者：

Choudhary, Garima ^{[1
]}

Peddinti, Rama Krishna ^{[1
]}

机构：

[1] Indian Inst Technol Roorkee, Dept Chem, Roorkee 247667, Uttarakhand, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 41期

关键词：

Catalyst-free; Solvent tuning; Ethyl lactate; Thiazolidinone; 1,3-Thiazinone; ACETYLENIC ESTERS; ETHYL LACTATE; GREEN SOLVENT; STEREOSELECTIVE-SYNTHESIS; ADDITION-REACTIONS; PRODUCTS; THIOUREA; ACETYLENEDICARBOXYLATE; CRYSTAL; ALKYL;

D O I：

10.1016/j.tetlet.2014.08.032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Green synthetic approach has been developed for the rapid generation of thiazolidinone derivatives as crystallized products under catalyst-free conditions in water by polarity adjustment with ethyl lactate as a co-solvent in excellent yields. Additionally, interesting findings on the synthesis of 2-amino-4H-1,3-thiazin-4-one and dimethyl 3,3'-thiodiacrylates have been reported. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：5597 / 5600

页数：4

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